Question

Propose one way to synthesize the products using Grignard reagent.

a) d) 9) ОН он ОН ОН b) ОН е) h) ОН с) ОН ОН f) ОН

Answer 1

If we add the Grignard reagent into the aldehyde, then we get the secondary alcohol.

If we add the Grignard reagent into the ketone, then we get the tertiary alcohol.

From the same all the product synthesis is easy and which is shown in given image.

Grignard Reaction : general Rean HO D R-mgre R -R1 R ether 2) 1200 a) OH Hit Dehy ng Br. product Ho 1) mgbr T OH X product 27 400 c) D CH ng Br tou product 2) hon PH d) 17 ch mg Br. 2) } pnpaid e D -mg Br 2) hoo product OH OB $) 1 mgbr product 2) Workies llo e- O product 11 mgbr 2) workup LOH product 1 CH₂ mgbr 2) Workeup