3. (5 pts) Rank the following alkyl bromides in order of reactivity using numbers 1-5 (1...
Rank the following alkyl bromides in order of decreasing reactivity to S2 substitution, by entering a ranking number (1-4) next to each structure (1=most reactive). Br-CHE Rank the following carbocations in order of decreasing stability, by entering a ranking number (1-3) in the space next to the structure (1-most stable). We were unable to transcribe this imageRank the following nucleophiles in decreasing order of nucleophilicity (most reactive first) in an aprotic solvent, by entering a ranking number (1-4) next to...
1. arrange Alkyl bromides in theoretical order of reactivity in SN1 reaction 2. arrange Alkyl bromides in theoretical order of reactivity in SN2 reaction AgNO3+ Ethanol Yal H₂C (SN 1) 1-Chlorobutane Nal + Acetone SN2 CH3 H3C 2-Chlorobutane Br CH3 H3C 2-Bromobutane CH3 H2C- a CH3 t-butylchloride Benzylchloride Br Bromobenzene
1. (2 point) Rank the following alkyl bromides from most reactive to least reactive in an S2 reaction. Explain your reasoning. a. 1-bromo-2methylbutane b. 1-bromo-3-methylbutane C. 2-bromo-2-methylbutane d. 1-bromopentane Most Reactive Least Reactive
5. Rank the reactivity of the following alkyl halides (A-E) for an SN2 reaction from the fastest (1) to the slowest (5) and explain your ranking. (10 pts) H3C-Br Br Ci
1a. Draw the two chair conformations for 1b. Draw the dominant frontier orbital interaction for the bromide in the reaction below. Which the SN2 reaction of NaCN with CH,Br. (Hint: the one do you think is more reactive? Why? HOMO of cyanide interacting with the LUMO of CH,Br). Clearly show the optimum alignment and NaCN + NaBr in-phase overlap of these orbitals. DMF 1e. Draw the enol intermediate in the 1d. Draw a specific example (reactants and products) hydration reaction...
Rank the following molecules in order of reactivity for an Sn2 substitution reaction (1 = most reactive, 4 = least reactive). ~ Br you d ora usea H3C-ci
15. Rank in order of Sn2 reactivity (1- most reactive) 16. Rank in order of leaving group ability (1- best leaving group) NH2 H20 CI 17. For each reaction, give the expected substitution product, and predict whether the mechanism will be predominantly first rder or second order. (a) 2-chloro-2-methylbutane CH3COOH (b) cyclohexyl bromide+ sodium ethoxide 18. Provide clear mechanism for the following reaction: CH2OCH3 Br CH3OH +HBr
6. (a) Rank the reactivity of the following alkyl halides (A-E) for an Syl reaction from the slowest (1) to the fastest(5) (b) Explain your ranking, (10 Pts Total) Cl CH3-Cl CH3 H,C
3. (3 pts) Rank the following compounds in order of reactivity with Bra in the presence of FeBrz. O Caico con Least Reactive Most Reactive 4. (9 pts) Give the structure of the major organic product formed in each of the following reactions. о он FeCl3 CH ΗΝΟ, H,SO
6. Rank the following alkyl halides based on the increasing reactivity for El reaction the least reactive to the most reactive) [2Pts] 7. Identify the product of the reaction between (R)-2-bromobutane and water. [2Pts] a. (S)-2-bromobutane b. [R]-2-bromobutane c. (S)-2-bromobutanol d. (R)-2-bromobutanol e. [R.S)-2-bromobutane f. [RS]-2-bromobutanol 8. Considering the Sx1, S2, E1, and E2 mechanisms, the energy diagram shown below corresponds to _ [2Pts] energy a. only the Sp1 mechanism b. only the E1 mechanism c. both the Sp1 and...