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Section: 12.3 GPCRS in Vision, Olfaction, and Gustation Section 12.4 21) Receptor tyrosine kinases: are dimers. e. f. do not regulate gene expression. g. engage in extensive cross talk with other signal transduction systems. h. bind insulin. Section: 12.4 Receptor Tyrosine Kinases Section 12.5 22) Protein kinase G: is activated by GMP. e. is a tyrosine kinase. is stimulated by sildenafil (Viagra). f. g. activates ion pumps in cardiac tiss h. Section: 12.5 Receptor Guanylyl Cyclases, CGMP, and Protein Kinase G does NOT activate guanylyl cyclase. 23) Atrial natriuretic factor Fibroblast growth factor e. f. g. Guanylin

Answer 1

21)

Ans-

Although all cell membranes receptors get and transmit signals from the environment, a portion of these receptors additionally doubles as enzymes. In such cases, the official of a flagging molecule to the layer receptor enacts the receptor's characteristic enzymatic movement. Of the different receptors that show this ability, receptor tyrosine kinases (RTKs) make up the biggest class. These phone surface receptors tie and react to development factors and other privately discharged proteins that are available at low focuses. RTKs assume significant jobs in the guideline of cell development, separation, and endurance.

When flagging particles tie to RTKs, they cause neighboring RTKs to connect with one another, shaping cross-connected dimers. Cross-connecting actuates the tyrosine kinase movement in these RTKs through phosphorylation — explicitly, each RTK in the dimer phosphorylates numerous tyrosines on the other RTK. This procedure is called cross-phosphorylation.