Question

Table 4: Agglutination reactions for Rh 12 marks ons for Rh [2 marks S Reaction to anti- Rh Rh Serum Mother present antigens Rh Type Douton Child 1 none Child 2 ador none Teaching Child 3 Rh reaction Answer the following questions: 0. Based on the results obtained explain the presence or absence of Rh antibodies in the mother prior to each pregnancy. [3 marks] 7. Is the mother right to be concerned about her third pregnancy? Explain. [2 marks] 6. Explain why Rh+ blood can be given only once to a non-sensitized person who is Rh-?! [2 marks] BIOL 20100 Lab 3 Protocol

Answer 1

6) in this case during the first pregnancy there is no significance of Rh antibodies because mother is Rh negative so mother doesn't have Rh antibodies. First child is also Rh negative so no significance

During second pregnancy, foetus is Rh positive, so there is significance of Rh antibodies because it is going to effect next child. Having no effect on this foetus.

During third pregnancy, Rh antibodies will already be present in mothers blood and they will cross placenta and have negative effects on foetus.

7) There are complications related to third pregnancy. During second pregnancy foetus was Rh positive, during parturition mother blood comes in contact with the Rh positive foetal blood. So mother body will start preparing antibodies against the Rh antigen .So during third pregnancy, foetus is Rh positive so antibodies are already present against Rh antigen, so they will cross placenta and have negative effects on foetus or may even kills the foetus.

8) Rh positive blood can be given to Rh negative person only one time because of Rh incompatibility.

During first blood transfusion when Rh positive blood is given, for the first time body faces Rh antigen, so the receiver body will form antibodies against Rh antigen. So during second blood transfusion, antibodies will be present and when blood will be transfused for second time, antibodies will destroy the RBC. So there is no use of blood transfusion.