Question

3. (10pts) The pregnancy drug Thalidomide is shown below. Draw both enantiomers of thalidomide. Label the configuration at each stereocenter as (R) or (S). Circle the enantiomer that was identified as toxic to pregnant mothers taking this drug to help with morning sickness around 1960. (2pts each enantiomer drawn correctly, 2pts for correct (R)/(S) label, 2pts for correct identity of toxic enantiomer) OX O H Thalidomide

Answer 1

(R (R)-Jhalidomida (S)-Jhalidomide Sedahve Jeratogenic enanHomar .