17-52 Show how you would synthesize the following compounds, starting with benzene or toluene and any necessary acyclic reagents. Assume para is the major product (and separable from ortho) in ortho, para mixtures.
1-phenyl-1-bromobutane
1-phenyl-1-methoxybutane
3-phenylpropan-1-ol
ethoxybenzene
1,2-dichloro-4-nitrobenzene
1-phenylpropan-2-ol
p-aminobenzoic acid
2-methyl-1-phenylbutan-2-ol
5-chloro-2-methylaniline
3-nitro-4-bromobenzoic acid
3-nitro-5-bromobenzoic acid
4-butylphenol
2-(4-methylphenyl)butan-2-ol
17-52 Show how you would synthesize the following compounds, starting with benzene or toluene and any...
1. Predict the major products formed when benzene reacts with the following reagents. (a). tert-butyl bromide, ALCl3 (b) bromine + a nail (c) iodine + HNO3 (d) carbon monoxide, HCl, and AlCl3/CuCl (e) nitric acid + sulfuric acid. 2. Predict the major products of the following reactions. (a.) nitrobenzene + ethyl chloride/AlCl3 (b). p-methylanisole + acetyl chloride + AlCl3 (c). nitrobenzene + fuming sulfuric acid (d) benzene + CH3CH2COCl in the presence of (1) ALCl3 followed by...
Starting with benzene as your only source of aromatic compounds, how would you synthesize the following substances? Assume that you can separate ortho and para isomers if necessary. p-Chlorotoluene m-Bromonitrobenzene o-Bromobenzenesulfonic acid m-Chlorobenzenesulfonic acid Starting with either benzene, phenol, or toluene, how would you synthesize the following substances? Assume that ortho and para isomers can be separated 2-Bromo-4-methylphenol 1,3,5-Trinitrobenzene 2,4,6-Tribromoaniline 2-Chloro-4-nitrotoluene
Show how you would synthesize each compound from benzene, toluene, or phenol using the following reactions: Reactions 1. Halogenation 2. Nitration 3. Sulfonation 4. Friedel-Crafts acylation 5. Friedel-Crafts alkylation 6. Oxidation of methyl group 7. Reduction of nitro group • Choose the starting material from the drop-down list • Enter the number(s) of the desired reactions in the order that you wish to use them without commas between • If a reaction is used more than once, enter its number...