1.) Please help me to figure out if this is the correct product, and if you could also give me an arrow pushing mechanism. (Salicylic Acid + Benzylamine reacting with EDCI, Cat. DMAP and DMF).
2.) What is the purpose of adding EDCI as a coupling reagent?
3.) Which groups in this reaction can undergo any type of covalent and/or non covalent interaction with any enzymes or receptors?
4.) What are at least two other side products other than the desired product of this reaction?
5.) Are there any other ways (please justify) to synthesize the product to get a higher yield and get fewer side products? Please show mechanism.
Homework Answers
Add Answer to:
1.) Please help me to figure out if this is the correct product,
and if you...
Started to work this problem out but i've gotten confused. May someone please show me the corrct mechanisms to complete...
Started to work this problem out but i've gotten confused. May
someone please show me the corrct mechanisms to complete these
questions? Thank you.
1. Give a complete curved-arrow mechanism for the reaction shown. Draw in any missing product structures. one other stereoisomer (draw in structure) 2. The ether shown, when reacting with excess HI gives the products shown. HO excess a. Give the complete curved-arrow mechanism for this reaction. b. Explain in about two sentences why this result is...
draw the major product of the reaction #1 and 2 below. please let me know how...
draw the major product of the reaction #1 and 2 below. please let
me know how i can get the product, i am confused in this process
t-BuOK DMF NaOH Ph DMF
please help!! this is all the info my hw gives me 5. Draw the product for...
please help!! this is all the info my hw gives me
5. Draw the product for each reaction below with an arrow pointing mechanism. a) NaCN DMSO b) O=o=0 DMF CH,COH 60°C
help please! 1) Reactions. Provide the major product for each reaction sequence, account for stereochemistry. 1)...
help please!
1) Reactions. Provide the major product for each reaction sequence, account for stereochemistry. 1) PCC, CH2Cl2 2) Brz, acetic acid OH 3) KotBu, A 4) NaOEt, EtOH P CO 8 5) H2O+ workup 6) THF, H.CaPPha HCB , cat. PdOAC) cat. PPh3, DMF, EN | CHA 0 нс. CH32) LDA, THF, -78 °C CHICH,then H3O+ workup 4) NaBH4, EtOH, then H3O+ workup 5) cat. TSOH, benzaldehyde 1) cat. H2SO4, A 2) O3. CH2Cl2, then (CH3)2S CH; 3) NaOE,...
Please help woth mechanisms and answers for these! 5. Shown below is the mechanism presented for...
Please help woth mechanisms and answers for these!
5. Shown below is the mechanism presented for the formation of biasplatin in reference 1 from the Experiment document. The amounts used of each reactant are shown. Either draw or describe a better alternative to this mechanism. (Note that the first step represents two steps combined and the proton loss is not even shown; fixing these is not the desired improvement.) 0.15 mmol 1.1 mmol 4. The acetylation of salicylic acid may...
if someone could please help me with this 6. Give the products from the following reactions....
if someone could please help me with this
6. Give the products from the following reactions. (6. points, 2 cach) но cat H 504 - HG 1. Propose a mechanism for the following reaction. Be sure to show the flow of electron with arrows and the structures of any reactive intermediates (6 points) I HO Cat. HySO4
I don't understand how to do these. Please help. thank you! 25. Draw the product of...
I
don't understand how to do these. Please help. thank you!
25. Draw the product of the following reaction: CH Bt 1. NaN, acetone 2.H30*, heat 26. Draw the product of the following reaction: C:03, H30* OH 27. Draw the product of the following reaction: CN 1. LiA1H, THF 2.H30* 28. Draw the product of the following reaction: CH,CHÚC CH3CH2CH2CHÖNH2 CH2CH3 SOCI, benzene heat 29. Draw the product of the following reaction: O=0 оо он + CH3COCCH3 NaOH H20 OH...
please help ? 25. Draw the product of the following reaction: CH,BE 1. N&CN, acetone 2....
please help ?
25. Draw the product of the following reaction: CH,BE 1. N&CN, acetone 2. H30, heat 26. Draw the product of the following reaction: CHOy, H,0* OH 27. Draw the product of the following reaction: CN 1. LiAH, THF 2.H309 28. Draw the product of the following reaction: CH3CH2CH2CHCNH, CH.CH SOCI), benzene heat 29. Draw the product of the following reaction: OO OH + CH3COCCH) NaOH H₂O ОН Salicylic acid lo-hydroxybenzoic acid) Acetic anhydride 30. Draw the product...
can you help me with these questions please For the reaction below, provide: • the CORRECT...
can you help me with these questions please
For the reaction below, provide: • the CORRECT IUPAC name for the starting material • a reasonable mechanism for the reaction • the reagents required • the by-product • the name given to this specific reaction
Orgo chem help please Fill in the major organic product or products for the following reactions....
Orgo chem help please
Fill in the major organic product or products for the following reactions. Make sure to indicate stereochemistry where appropriate. Label each reaction with the mechanism used to get to the product (SN1, SN2, etc) Br H2O Br Br Br Br Br OH Heat Br Draw the complete mechanism for the first reaction (as practice you should draw the mechanism for all of them, based on what we learned in class)
Started to work this problem out but i've gotten confused. May
someone please show me the corrct mechanisms to complete these
questions? Thank you.
1. Give a complete curved-arrow mechanism for the reaction shown. Draw in any missing product structures. one other stereoisomer (draw in structure) 2. The ether shown, when reacting with excess HI gives the products shown. HO excess a. Give the complete curved-arrow mechanism for this reaction. b. Explain in about two sentences why this result is...
draw the major product of the reaction #1 and 2 below. please let
me know how i can get the product, i am confused in this process
t-BuOK DMF NaOH Ph DMF
please help!! this is all the info my hw gives me
5. Draw the product for each reaction below with an arrow pointing mechanism. a) NaCN DMSO b) O=o=0 DMF CH,COH 60°C
help please!
1) Reactions. Provide the major product for each reaction sequence, account for stereochemistry. 1) PCC, CH2Cl2 2) Brz, acetic acid OH 3) KotBu, A 4) NaOEt, EtOH P CO 8 5) H2O+ workup 6) THF, H.CaPPha HCB , cat. PdOAC) cat. PPh3, DMF, EN | CHA 0 нс. CH32) LDA, THF, -78 °C CHICH,then H3O+ workup 4) NaBH4, EtOH, then H3O+ workup 5) cat. TSOH, benzaldehyde 1) cat. H2SO4, A 2) O3. CH2Cl2, then (CH3)2S CH; 3) NaOE,...
Please help woth mechanisms and answers for these!
5. Shown below is the mechanism presented for the formation of biasplatin in reference 1 from the Experiment document. The amounts used of each reactant are shown. Either draw or describe a better alternative to this mechanism. (Note that the first step represents two steps combined and the proton loss is not even shown; fixing these is not the desired improvement.) 0.15 mmol 1.1 mmol 4. The acetylation of salicylic acid may...
if someone could please help me with this
6. Give the products from the following reactions. (6. points, 2 cach) но cat H 504 - HG 1. Propose a mechanism for the following reaction. Be sure to show the flow of electron with arrows and the structures of any reactive intermediates (6 points) I HO Cat. HySO4
I
don't understand how to do these. Please help. thank you!
25. Draw the product of the following reaction: CH Bt 1. NaN, acetone 2.H30*, heat 26. Draw the product of the following reaction: C:03, H30* OH 27. Draw the product of the following reaction: CN 1. LiA1H, THF 2.H30* 28. Draw the product of the following reaction: CH,CHÚC CH3CH2CH2CHÖNH2 CH2CH3 SOCI, benzene heat 29. Draw the product of the following reaction: O=0 оо он + CH3COCCH3 NaOH H20 OH...
please help ?
25. Draw the product of the following reaction: CH,BE 1. N&CN, acetone 2. H30, heat 26. Draw the product of the following reaction: CHOy, H,0* OH 27. Draw the product of the following reaction: CN 1. LiAH, THF 2.H309 28. Draw the product of the following reaction: CH3CH2CH2CHCNH, CH.CH SOCI), benzene heat 29. Draw the product of the following reaction: OO OH + CH3COCCH) NaOH H₂O ОН Salicylic acid lo-hydroxybenzoic acid) Acetic anhydride 30. Draw the product...
can you help me with these questions please
For the reaction below, provide: • the CORRECT IUPAC name for the starting material • a reasonable mechanism for the reaction • the reagents required • the by-product • the name given to this specific reaction
Orgo chem help please
Fill in the major organic product or products for the following reactions. Make sure to indicate stereochemistry where appropriate. Label each reaction with the mechanism used to get to the product (SN1, SN2, etc) Br H2O Br Br Br Br Br OH Heat Br Draw the complete mechanism for the first reaction (as practice you should draw the mechanism for all of them, based on what we learned in class)
Most questions answered within 3 hours.
-
After watching the lectures I am still having a hard time
understanding these equations.
1. The...
asked 55 minutes ago -
Testing:
H0:μ=56.9
H1:μ<56.9
Your sample consists of 23 subjects, with a mean of 56.3 and
standard...
asked 58 minutes ago -
straight wire, labeled as Wire A, lies horizontally on a
tabletop and is oriented to run...
asked 59 minutes ago -
For a Chi-Squared Goodness of Fit Test about a uniform
distribution, complete the table.
Round to...
asked 1 hour ago -
Milk of magnesia is only slightly soluble in water. Kc for the
reaction Mg(OHs)(s)>Mg2+(a) + 2OH-1(aq)...
asked 1 hour ago -
Excel's HYPGEOM.DIST function can be used to compute _____.
a. both hypergeometric probabilities and cumulative
hypergeometric...
asked 1 hour ago -
The rocket used for the human lunar missions was the Saturn V
rocket. At liftoff the...
asked 1 hour ago -
1. The East Street Bagel Shop has a weekly demand for 3,500
bagels, which they make...
asked 1 hour ago -
paraphrasing each paragraph
“Where two or more persons knowingly act together unlawfully,
the act of each...
asked 1 hour ago -
The lateral line system in fish is contained which of the
following?
chemoreceptors
photoreceptors
mechanoreceptors
odor...
asked 1 hour ago -
Find the y-intercept of y =-5 x. The y-intercept of y equals
negative 5 x is______...
asked 1 hour ago -
Customers arrive randomly at a gas station at the average rate
of 30 per hour, while...
asked 1 hour ago