Question

Colony-stimulating factors are hormones that regulate hematopoiesis. Erythropoietin (Epogen), secreted by the kidney, increases bone marrow erythropoiesis. Granulocyte colony-stimulating factor (G-CSF) stimulates bone marrow leukopoiesis. The most recent colony-stimulating factor is thrombopoietin (TPO), which acts on bone marrow to promote the growth of platelets. These hormones are now produced biosynthetically by recombinant DNA techniques and have shown some impact in the prevention of chemotherapy-induced neutropenia, treatment of cytopenias associated with myelodysplasias, and aplastic anemia. 1. What is erythropoietin? A. A drug that causes bone marrow suppression B. A chemical that promotes white cell production C. A recombinant product that stimulates platelet growth D. A renal hormone that stimulates growth of RBCS 2. G-CSF is helpful in: A. Preventing decrease in WBCs during drug treatment for cancer B. Replacing red cells after hemorrhage C. Stimulating formation of thrombocytes D. Stimulating lymphocytes 3. Myelodysplasia means: A. The spleen is not functioning B. Liver formation is impaired C. Blood cells are not made D. The bone marrow is not forming blood cells properly 4. TPO is: A. A neutrophil growth factor B. An erythrocyte growth factor C. A clotting cell growth factor useful in the treatment of thrombocytopenia D. Useful in the treatment of hemophilia

Answer 1

1. Answer ; D) a renal hormone that stimulate growth of RBC

Reason; In the given context, its been given that it is useful for the erythropoiesis. The only option that explain the proper meaning of the term would be the above mentioned option.

2. Answer ; A) Preventing the decrease of WBCs during the drug treatment of cancer.

Reason ; The term asked in the question is useful to increase the WBCs formation, hence it prevent the decrease of WBC during the treatment process.

3. Answer ; D) Bone marrow is not forming blood cells properly.

Reason ; The given medical term is related to the bone marrow. The other option are associated with the other part of the body. hence the above option is the most appropriate one.

4. Answer ; C) a clotting cell growth factor useful in the treatment of thrombocytopenia.