Homework Answers
ANSWER PART 1. (UPLOADED PICTURE)
ANSWER PART 2. (UPLOADED PICTURE)
ANSWER PART 3: PKa value is used to determine the strength of an acid. The lower the PKa value, the stronger the acid.
Alcohol has a PKa value of 15(approximate)
2-Azetidinone ( functional group in Ezetimibe) has a PKa value of 11.3 (approximate)
2-Aminoimidazole ( functional group in Clonidine) has a PKa value of 8.5(approximate)
ANSWER PART
4: The 2-Aminoimidazole (functional group in
Clonidine) is the most basic of all because of presence of 3
Nitrogen groups. It is a derivative of a strong base guanidine
.
Examples Benzocaine pka = SON HEN CHER Cephalexin NH3 What is the most dominant species at...
Examples Benzocaine pka = SON HEN CHER Cephalexin NH3 What is the most dominant species at pH 7.4? рка = -> H+ TV For each: •Give the functional group name, hybridization and acidity (Acidic, Basic or Neutral) of the circled atoms •Give the most likely basic form in water •Estimate the pka of circled atoms •Which one is the stronger acid (blue circle) 118
please thoroughly explain Benzocaine pka = → H+ + Cephalexin NH pka = What is the...
please thoroughly explain
Benzocaine pka = → H+ + Cephalexin NH pka = What is the most dominant species at pH 7.4? H+ + → For each: Give the functional group name, hybridization and acidity (Acidic, Basic or Neutral) of the circled atoms Give the most likely basic form in water •Estimate the pka of circled atoms •Which one is the stronger acid (blue circle) 118
please thoroughly explain Phentolamine What is the most dominant species at pH 7.4? pka = a...
please thoroughly explain
Phentolamine What is the most dominant species at pH 7.4? pka = a > H+ + НАС Verapamil pka = pKa = > H K H₃ C CH₃ → H CH,CO háchoenen OCH HCO OCH3 For each: Give the functional group name, hybridization and acidity (Acidic, Basic or Neutral) of the circled atoms •Give the likely conjugate acid form in water •Estimate the pka of circled atoms •Which one is the stronger base (blue circle) 121
PS questions 1. (2 pt) Which is the correct structure for (R)-N-ethyl-3-methylcyclopent-2-en-1-amine? A INHEt Et >...
PS questions 1. (2 pt) Which is the correct structure for (R)-N-ethyl-3-methylcyclopent-2-en-1-amine? A INHEt Et > NHEN VEt | ANH NHA | NHẤt A 2. (2 pt) Which is the correct name for the structure? HN1 A. (4R,7R)-4-(3-methoxyphenyl)-N-methyloctan-7-amine B. (48,7R)-4-(3-methoxyphenyl)-N-methyloctan-7-amine C. (2R,5S)-5-(3-methoxyphenyl)-N-methyloctan-2-amine D. (2R,5R)-5-(3-methoxyphenyl)-N-methyloctan-2-amine OMe 3. (3pt) Why is HONH2 more basic? Note the pka values are for the conjugate acids. HONH2 ZI A. diphenylamine has more resonance structure after protonation B. the Nitrogen electrons on diphenylamine can resonanate into...
can’t figure any of this out, please help all of it 1-5. Match the functional group...
can’t figure any of this out, please help all of it
1-5. Match the functional group indicated by the arrow to the correct classification Quinine used to treat malaria 2. OH Hºme Church Hyco-OH Nysatin A, 3. CH, CH, OH A) primary alcohol B) secondary alcohol C) tertiary alcohol D) phenol E) thiol сн, он CH, OH не OH CONH2 -OH Tetracycline, an antibiotic 6-10. Given the following list of acid strengths of some medications, match the acid to the...
1. (6 pts total; 2 pts each) Proteins that catalyze chemical reactions in living systems are...
1. (6 pts total; 2 pts each) Proteins that catalyze chemical reactions in living systems are called enzymes. The basic building blocks of proteins are called amino acids and have the general structure pictured below, left, where R is a substituent containing one of many organic functional groups. Some representative examples of amino acids found in nature are pictured here as well (R groups only) сн. н 0:00 HO-C-H. HỌC-C-CH, CH,SH H-C-H H2N -CO,H H An Amino Acid Threonine Valine...
I posted a question and received a partial answer 1-5, would like the entire question answered please. 1-5. Mat...
I
posted a question and received a partial answer 1-5, would like the
entire question answered please.
1-5. Match the classifications (A-E) to the correct functional group in these compounds. 2. 3. 4. 5. но но SH Он но E A E) tertiary alcohol A) phenol B) thiol C) primary alcohol D) secondary alcohol 6-10. Identify the following as acidic, basic, or neutral Questions 6. Seawater [HO] =5.3 x 10 7. Saliva pH = 6.5 8. Sour Cherries 9. Rain...
Need help with my homework thats due tonight, havent had time to get to tudoring. Please...
Need help with my homework thats due tonight, havent had time to
get to tudoring. Please help have 5 other assignments due as well.
All questions please 1-25
1-5. Match the classifications (A-E) to the correct functional group in these compounds. SH НО OH A) phenol Bthiol C) primary alcohol D) secondary alcohol tertiary alcohol 6-10. Identify the following as acidic, basic, or neutral Questions 6. Seawater (H30) -5.3 x 10 7. Saliva pH = 6.5 8. Sour Cherries 9....
(6 pts total: 2 pts each) Proteins that catalyze chemical reactions in living systems are called...
(6 pts total: 2 pts each) Proteins that catalyze chemical reactions in living systems are called enzymes. The basic building blocks of proteins are called amino acids and have the general structure pictured below, left, where R is a substituent containing one of many organic functional groups. Some representative examples of amino acids found in nature are pictured here as well (R groups only) O . CH, HO-C-H H-C-H HẠC-C-CH, CH,SH HNT-CO,H Cysteine Valine Threonine Aspartic Acid An Amino Acid...
12. Below is a portion of the abstract of a journal article. It describes the isolation,...
12. Below is a portion of the abstract of a journal article. It describes the isolation, purification, and determination of the peptide sequence as well as, the location of each of the disulfide bridges of an antibacterial peptide from the cowpea plant. Give brief and to the point answers to the questions based upon this information. (2 pts) FEBS Joumal 273 (2006) 3489-3497 2006 The Authors Journal compilation2006 FEBS Identification of a cowpea y-thionin with bactericidal activity Octávio L. Franco,...
Examples Benzocaine pka = SON HEN CHER Cephalexin NH3 What is the most dominant species at pH 7.4? рка = -> H+ TV For each: •Give the functional group name, hybridization and acidity (Acidic, Basic or Neutral) of the circled atoms •Give the most likely basic form in water •Estimate the pka of circled atoms •Which one is the stronger acid (blue circle) 118
please thoroughly explain
Benzocaine pka = → H+ + Cephalexin NH pka = What is the most dominant species at pH 7.4? H+ + → For each: Give the functional group name, hybridization and acidity (Acidic, Basic or Neutral) of the circled atoms Give the most likely basic form in water •Estimate the pka of circled atoms •Which one is the stronger acid (blue circle) 118
please thoroughly explain
Phentolamine What is the most dominant species at pH 7.4? pka = a > H+ + НАС Verapamil pka = pKa = > H K H₃ C CH₃ → H CH,CO háchoenen OCH HCO OCH3 For each: Give the functional group name, hybridization and acidity (Acidic, Basic or Neutral) of the circled atoms •Give the likely conjugate acid form in water •Estimate the pka of circled atoms •Which one is the stronger base (blue circle) 121
PS questions 1. (2 pt) Which is the correct structure for (R)-N-ethyl-3-methylcyclopent-2-en-1-amine? A INHEt Et > NHEN VEt | ANH NHA | NHẤt A 2. (2 pt) Which is the correct name for the structure? HN1 A. (4R,7R)-4-(3-methoxyphenyl)-N-methyloctan-7-amine B. (48,7R)-4-(3-methoxyphenyl)-N-methyloctan-7-amine C. (2R,5S)-5-(3-methoxyphenyl)-N-methyloctan-2-amine D. (2R,5R)-5-(3-methoxyphenyl)-N-methyloctan-2-amine OMe 3. (3pt) Why is HONH2 more basic? Note the pka values are for the conjugate acids. HONH2 ZI A. diphenylamine has more resonance structure after protonation B. the Nitrogen electrons on diphenylamine can resonanate into...
can’t figure any of this out, please help all of it
1-5. Match the functional group indicated by the arrow to the correct classification Quinine used to treat malaria 2. OH Hºme Church Hyco-OH Nysatin A, 3. CH, CH, OH A) primary alcohol B) secondary alcohol C) tertiary alcohol D) phenol E) thiol сн, он CH, OH не OH CONH2 -OH Tetracycline, an antibiotic 6-10. Given the following list of acid strengths of some medications, match the acid to the...
1. (6 pts total; 2 pts each) Proteins that catalyze chemical reactions in living systems are called enzymes. The basic building blocks of proteins are called amino acids and have the general structure pictured below, left, where R is a substituent containing one of many organic functional groups. Some representative examples of amino acids found in nature are pictured here as well (R groups only) сн. н 0:00 HO-C-H. HỌC-C-CH, CH,SH H-C-H H2N -CO,H H An Amino Acid Threonine Valine...
I
posted a question and received a partial answer 1-5, would like the
entire question answered please.
1-5. Match the classifications (A-E) to the correct functional group in these compounds. 2. 3. 4. 5. но но SH Он но E A E) tertiary alcohol A) phenol B) thiol C) primary alcohol D) secondary alcohol 6-10. Identify the following as acidic, basic, or neutral Questions 6. Seawater [HO] =5.3 x 10 7. Saliva pH = 6.5 8. Sour Cherries 9. Rain...
Need help with my homework thats due tonight, havent had time to
get to tudoring. Please help have 5 other assignments due as well.
All questions please 1-25
1-5. Match the classifications (A-E) to the correct functional group in these compounds. SH НО OH A) phenol Bthiol C) primary alcohol D) secondary alcohol tertiary alcohol 6-10. Identify the following as acidic, basic, or neutral Questions 6. Seawater (H30) -5.3 x 10 7. Saliva pH = 6.5 8. Sour Cherries 9....
(6 pts total: 2 pts each) Proteins that catalyze chemical reactions in living systems are called enzymes. The basic building blocks of proteins are called amino acids and have the general structure pictured below, left, where R is a substituent containing one of many organic functional groups. Some representative examples of amino acids found in nature are pictured here as well (R groups only) O . CH, HO-C-H H-C-H HẠC-C-CH, CH,SH HNT-CO,H Cysteine Valine Threonine Aspartic Acid An Amino Acid...
12. Below is a portion of the abstract of a journal article. It describes the isolation, purification, and determination of the peptide sequence as well as, the location of each of the disulfide bridges of an antibacterial peptide from the cowpea plant. Give brief and to the point answers to the questions based upon this information. (2 pts) FEBS Joumal 273 (2006) 3489-3497 2006 The Authors Journal compilation2006 FEBS Identification of a cowpea y-thionin with bactericidal activity Octávio L. Franco,...
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