5. Using bromobenzene, cyclohexene and vinyl bromide as your source of carbons, outline a synthesis of...
5. Using bromobenzene, cyclohexene and vinyl bromide as your source of carbons, outline a synthesis of 1-cyclohexyl-2-phenylethanol which is used to reduce irritation in transdermal drug delivery (15 pt)
N H OH H2O OHO Ising hromobenzene, cyclohexene and vinyl bromide as your source of carbons, outline a
Name 4. Starting with cyclohexene and acetylene as the only source of carbons, show a synthesis of the compound below. 1. Show how you could make the given product from the given starting material. Show all steps. OH a CECH 2. Starting with acetylene and methyl bromide as your only source of carbons show a synthesis of cis-2-butene. 5. Prepare 2-methoxy-propanol from 1-bromo-propane. Show the steps and use any reagents you need. 3. Using acetylene and propyl bromide as your...
Question 6. (14 marks) Using reactions taught in class, outline a synthesis to produce 3,8-dimethyldecan- 4,7-diol shown below. You may only use 2-bromobutane as a carbon source for your synthesis, but you may use any inorganic reagents you wish for the synthesis, which will require several steps. For full marks, provide the reagents to each step, and provide each compound synthesized in the production of the final target molecule. You may ignore stereochemistry for this question. If you need extra...
14. Indicate the steps required for the synthesis of the product using bromobenzene: H3C OH Br - 15. Write the complete stepwise mechanism for the reaction. Show all intermediate structures and all electron flow with arrows. OH O-CH3 1. NaH 2.CH3l, ether
Integrated Problem 09.64 Using acetylene and methyl bromide as your only sources of carbon atoms, propose a synthesis for the following compound: + En A Choose from the following list of reagents (A-H): 1) Br2 2) Excess H20 3) NaNH2 1) H2, Lindlar's catalyst 2) HBr 1) NaNH2 2) EtBr 3) Na, NH3 (1) 4) MeBr 1) NaNH2 2) EtBr 3) NaNH2 4) MeBr H 1) Na, NH3 (1) 2) MCPBA 1) NaNH2 2) EtBr 3) H2, Pt 1) H2,...
Question 5: Outline a synthesis for any Two of the following four synthetic transformations. In your answer you should provide all reagents required to effect each transformation and the structures of any neutral intermediate compounds [only the first two answers will be graded] 16 pts, 8 pts each OH 1. a 2. COOH COOH 3. B! HOOC
stepwise synthesis for N-propylbutanamide using 1-propanol and/or carbon dioxide as your only source of carbon Use Using the reagents below, list in order (by letter, no period) those necessary to provide this synthesis. Note: Not all spaces provided may be needed. Hints: First receive a Grignard reagent in steps 1 and 2. Use propanol in step 5. In step 9 a product from step 4 reacts with a product from step 8. a. NH3 b. Mg/ether c. SOCl2 d. 1....
Seco te Spaces provided.) 1. The following reaction is an example of a hydrovin ylation reaction The synthesis involves the use of a catalyst, PdHCI(PCy3) (shown below), with an outline of the catalytic cycle showing all the complexes involve: EC 6. PCy3 Product Clon PetaPCy EC 5. 2. EC = PCy Clton 3. a. The catalytic cycle involves 6 steps, which could be any of the follo () Ligand dissociation (i)i. Migratory insertion (ii) Ligand ad (iv). b-hydride elimination (v)....
Question 3 Propose a stepwise synthesis for N-propylbutanamide, using 1-propanol and/or carbon dioxide as your only source of carbon and any other reagents necessary. Testbank, Question 140a Using the reagents below, list in order (by letter, no period) those necessary to provide this synthesis Note: Not all spaces provided may be needed. Hints: First receive a Grignard reagent in steps 1 and 2. Use propanol in step 5. In step 9 a product from step 4 reacts with a product...