Question

- - - - - - -- - - - - -- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 100 mL յա 7 USUAL DOSAGE 6 to 40 million units daily by intravenous infusion only Rx only NDC 0049-0530-28 Buffered Pfizerpen (penicillin G potassium) 75 ml SEE ACCOMPANYING PRESCRIBING INFORMATION. RECOMMENDED STORAGE IN DRY FORM. Store below 86-F (30-C). Buffered with sodium citrate and citric acid to optimum pH. AFTER RECONSTITUTION, SOLUTION SHOULD BE REFRIGERATED. DISCARD UNUSED SOLUTION AFTER 7 DAYS. APPROX. VOLUME SCALE ml diluent added 75 mL 33 mL 11.5 mL Approx. units per mL of solution 250 000 u/ml 500.000 u/ml 1,000,000 u/mL juos For Injection PATIENT TWENTY MILLION UNITS ROOM APPROX. VOLUME SCALE 50 ml 7 SL 05-4211-321 FOR INTRAVENOUS INFUSION ONLY DATE_ TIME BY Pfizer Roerig 7488 25 ml Division of terhe, NY, NY 10017 TWOOL - - - - - - -- - - - - - - - -- - - - - - - - -- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -- 4. If the vial of Penicillin G Potassium is reconstituted with 33ml of diluent, how many mL would be added to each bag for a dose of 6 million units?_ 5. A prescription calls for 4 million units per dose. The patient will receive the dose every 4 hours. If you make a 3-day supply for the patient, how many vials will be needed? 6. How many mL of drug will be place in each individual bag from question 5 if the vial is reconstituted with 75ml?

Answer 1

No 4.

20 million units Penicillin G Potassium in 33ml.

Desire dose 6 million units Pennicilin G Potassium.

$\large 33ml\div 20mu=1.65ml$

1.65 ml of dilutant contains 1 million units Penicillin G Potassium.

$\large 1.65ml\times 6mu=9.9ml$

Answer- 9.9ml would be added to each bag for a dose of 6 million units Penicillin G Potassium.

No 5.

Desire dose 4 million units Penicillin G Potassium 6 times a day(In every 4 hours).

$\large 4mu\times 6 times= 24mu$

So, the daily needed dose will be  24 million units Penicillin G Potassium.

$\large 24mu\times 3days=72mu$

In 3 days patient needed a total of 72 million units of Penicillin G Potassium.

1 vial of Penicillin G Potassium contains 20 million.

Answer -  4 vials needed for 3days.

No 6.

Desire dose 4 million units Penicillin G Potassium in a single dose.

The total strength is 20 million units in 75 ml.

$\large 75ml\div 20mu=3.75ml$

I.e 3.75ml dilutant contain 1 million units Penicillin G Potassium.

We have to add 4 million units of Penicillin G Potassium in each bag.

$\large 4mu\times 3.75ml=15ml$

I.e 15ml contains 4 million units Penicillin G Potassium.

Answer - 15ml of the drug will be placed in each individual bag for a single dose if the vial is reconstituted with 75ml of dilutant.