Draw the mechanism for the formation of anhydride starting with 2 equivalents of carboxylic acid, using DCC as the dehydrating reagent
Draw the mechanism for the formation of anhydride starting with 2 equivalents of carboxylic acid, using...
9. In this laboratory experiment, you use excess carboxylic acid (2.4 equivalents). Therefore, when the reaction is complete, you will have some carboxylic acid along with your ester as the product. Answer the following questions: (a) How was this excess carboxylic acid removed from your ester product? To answer this question, answer the two parts below. (i) Draw the reaction that allows for the excess carboxylic acid to be removed below. You must show the starting materials of the reaction,...
A carboxylic acid derivative reacts to yield products mentioned on the scheme. Suggest starting carboxylic acid derivative and the reaction conditions for each reaction. Reagent Carboxylicacid derivative Carboxylicacid derivative ile Carboxylicacid derivative Which molecule played a Carboxylicacid derivative Which molecule played a le Carboxylic acid derivative 2,3-dimethyl butanoic anhydride iso-propoxide leaving group concentrated HCI nitrile iso-propyl 2,3-dimethyl butanoate 2 chloride No base iso-propyl amine
Phenolphthalein is synthesized by the acid-catalyzed reaction of
phthalic anhydride with 2 equivalents of phenol. Propose and
illustrate a mechanism for the reaction in the presence of sulfuric
acid and heat.
OH
In the mechanism for formation of acetylsalicylic acid via reaction of salicylic acid with acetic anhydride, phosphoric acid acts as a catalyst by O cleaving an acetyl group from acetic anhydride via protonation of the bridging oxygen O neutralizing the hydroxide ion side product protonating the carbonyl oxygen in the acetic anhydride protonating the phenolic oxygen of salicylic acid Question 10 (3 points) What would be the predicted major product from the thermodynamically controlled dehydration of the following material OH
Draw a mechanism for the formation of menthyl chloride from
menthol using HCl as a reagent. Use curly arrows to indicate
movement of electrons. What is the name of this mechanism? Finally,
draw a reaction energy diagram for the formation of the product.
Pay close attention to the relative energy levels of the starting
material, product, and any intermediates that may form.
HCI OH menthol menthyl chloride
2. If one were esterifying an expensive alcohol with an expensive carboxylic acid derivative, would it be wiser to use the acid chloride or acid anhydride reagent? Why? 3. Why is so much NaOH used in the extraction? Recall that only four drops (small amount) of sulfuric acid were used as a catalyst. Esters are an important class of organic molecules, which are formally derived from alcohols and carboxylic acids. Esters occur widely in nature and are often an important...
1. Answer three of the following flve parts (U)(v): Acid Chloride Carboxylic acid Anhydride (a) Choose one reaction given above used to prepare A and outline the mechanism. [4 Marks] DOLL
The reaction mechanism for the conversion of maleanilic acid to N-phenylmaleimide (24B) proceeds through formation of a mixed anhydride intermediate (not isolated). a) Draw the chemical structure of the mixed anhydride intermediate. b) Write a mechanism for the conversion of the mixed anhydride to N-phenylmaleimide. Be as complete as possible and show electron flow for all steps.
Chem 202, Fall 2019 Homework Packet 9 (Carboxylic Acid Derivatives) 2. Reactivity of Carboxylic Acid Derivatives a. Rank the following carboxylic acid derivatives in order from LEAST reactive to MOST reactive when they undergo nucleophilic acyl substitution reactions: — '— ' la do lan loons obe OCH3 b. Justify your answer thoroughly in words. Your explanation should include, if applicable, definitions and explanations that cover leaving group ability, conjugate acid strengths, pKa values, etc. 4. Amide Formation Mechanism: Draw the...
Question 3 Consider the reaction shown below. CEN ОК KOH H20 Propose a detailed mechanism using curved arrows in a step by step manner to illustrate the formation of the carboxylic acid salt formed in this reaction. Make sure to use curved arrows to show the deprotonation, protonation, bonds formation or bonds cleavage.