Phenolphthalein is synthesized by the acid-catalyzed reaction of phthalic anhydride with 2 equivalents of phenol. Propose and illustrate a mechanism for the reaction in the presence of sulfuric acid and heat.
Phenolphthalein is synthesized by the acid-catalyzed reaction of phthalic anhydride with 2 equivalents of phenol. Propose...
Reaction A: Resorcinol + Phthalic Anhydride ---(H2SO4)---> Fluorescein (2) C6H6O2 + C8H4O3 ---(H2SO4)---> C20H12O5 Reaction B: 3-(dimethylamino)-phenol + Phthalic Anhydride ---(H2SO4)--> Rhodamine B (2) C8H11NO + C8H4O3 ---(H2SO4)---> C28H31ClN2O3 This reaction involves two subsequent Friedel-Crafts acylation reactions. What is the structure of the intermediate after the first Friedel-Crafts reaction?
Reaction A Xanthene Dye Resorcinol = 0.159 g Phthalic anhydride = 0.103 g Final weight = 0.173 g Amount used for UV = 3 mg Reaction B 3-(diethylamino)-phenol Phthalic anhydride = 0.102 g 3- (diethylamino)-phenol: 0. 230 g Final weight: 0.245 g Amount used for UV: 3 mg 1. Draw the exact stoichiometric reactions for each. 2. What is the theoretical weight expected for your dye synthesis?
Show the mechanism of the acid catalyzed reaction of an alcohol with acetic anhydride, indicating the involvement of the strong acid catalyst in the reaction. H2SO4 (cat.) R'OH ROR ROH ROD +
Provide the product for the following reaction. Propose an acid catalyzed mechanism for this reaction. Specify if this reaction is general acid or specific acid catalyzed reaction. Draw free energy diagram for this reaction based on your mechanism. Make sure to include reaction intermediates in your free energy diagram (12 points total) NH 2 pH 3
Predict the major product of the acid-catalyzed dehydration of 2,2-dimethyl-1-hexanol. Then propose a mechanism with curved arrows of this reaction. 20) Predict the major product of the acid-catalyzed dehydration of 2.2-dimethyl-1-hexanol. Then propose a mechanism with curved arrows of this reaction. H2SO4 LOH heat
propose a stepwise mechanism for the acid- catalyzed reaction shown below OH noin 10 sexo en el aasd 525 is al woladincluso Tower H2SO4 4 Sheen H2O oluline on
Propose a stepwise mechanism for the acid-catalyzed reaction shown below. OH + H₂O H2SO4 Attach File Browse My Computer Browse Content Collection Browse Drop!
propose a stepwise mechanism for the acid-catalyzed reaction shown below OH noin 10 nisexo ert eisad 5 26 ppilas al wolodinwo sluoriin Tower H2SO4 l Sheparo Vet H20consen (2tube on
propose a stepwise mechanism for the acid-catalyzed reaction shown below OH noin 10 nisbyxo ert eisad 5 25 Onios ai wolodinwoolused on Tower H2SO4 Sheparo) Vet H20 e conseno (etului on
Salicylic acid and acetic anhydride are synthesized with phosphoric acid to catalyze the reaction to make acetylsalicylic acid (aspirin). How will you know if you have successfully synthesized acetylsalicylic acid? What compound will you have if you did NOT successfully synthesize acetylsalicylic acid, and how can you confirm it?