Inheritance pattern in BRCA 1 Describe the inheritance pattern of BRCA 1 Is it recessive or...
Inheritance pattern in BRCA 1
Describe the inheritance pattern of BRCA 1 Is it recessive or
dominant? Autosomal or sex- linked? Be sure to describe the
genotypes and phenotypes of both the affected individuals and their
parents. Are there any non-Mendelian inheritance patterns involved
(e.g., co-dominance or incomplete dominance)? what does this
inheritance pattern mean for individuals who have the mutated gene?
use at least one diagram and text to convey this information. A
pedigree chart is often a useful figure to include, but whatever
type of diagram you use, you must be sure to cite the figure in the
text, and explain the figure’s relevance. pls provide source
because I can't find anything helpful
Homework Answers
Mutations in the BRCA1 and BRCA2 genes are inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to develop breast cancer.
Aa x aa
Affected x unaffected
| A | a | |
| a | Aa | aa |
| a | Aa | aa |
If one parent is suffering from BRCA1 mutation he or she can have Aa genotype and the other parent is normal then 50% of the children will remain affected and 50% of the children will be normal.
No non-Mendelian inheritance patterns involved here.
Pedigree of BRCA1 affected family-
Add Answer to:
Inheritance pattern in BRCA 1
Describe the inheritance pattern of BRCA 1 Is it recessive or...
Web Genotypes and phenotypes for some common single gene inheritance patterns. Inheritance Pattern Genotype Phenotype Affected...
Web Genotypes and phenotypes for some common single gene inheritance patterns. Inheritance Pattern Genotype Phenotype Affected Affected Not affected AA Autosomal Dominant Aa aa NN Not affected Not affected Affected Autosomal Recessive Nn nn XXN XNX Normal female Normal female Affected female Normal male Affected male Sex-linked Recessive X"X xNY X"Y Pedigree Analys is Instructions: 1. Examine the following three pedigrees. 2. Determine the most probable pattern of inheritance for each pedigree and record it in the space provided at...
. O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree...
. O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree charts on the following page, determine which pattern of inheritance most likely explains the observed pattern of traits in the family shown. Observe the general patterns in the pedigree charts on the following page o males vs females? parents with disease? Compare these patterns with the clues on the previous page to hypothesize a pattern of inheritance Based on this pattern of inheritance, use...
Review This pedigree shows the inheritance pattern of a recessive maternal effect gene in Drosophila. In...
Review This pedigree shows the inheritance pattern of a recessive maternal effect gene in Drosophila. In maternal effect, the offspring's phenotype is under the control of nuclear gene products present in the mother's egg. In this example, the presence of the at allele in the mother is required for proper wing development in the offspring. Submit Previous Answers Correct In the pedigree, individuals who are wingless are indicated by a shaded symbol. The phenotypes and genotypes are only provided for...
PEDIGREES When a trait follows Mendelian inheritance it is often possible to figure out its dominance...
PEDIGREES When a trait follows Mendelian inheritance it is often possible to figure out its dominance state by using a pedigree. Below are four pedigrees for four different traits. They are all autosomal traits (meaning they are not inherited on the X or Y chromosomes). For each trait, determine if it is dominant, recessive or unable to be determined. And explain each answer If it helps your explanation, you may label the symbols with letters Remember squares are males, circles...
II Review a tla + This pedigree shows the inheritance pattern of a recessive maternal effect...
II Review a tla + This pedigree shows the inheritance pattern of a recessive maternal effect gene in Drosophila. In maternal effect, the offspring's phenotype is under the control of nuclear gene products present in the mother's egg. In this example, the presence of the a + allele in the mother is required for proper wing development in the offspring. a tla a/a In the pedigree, individuals who are wingless are indicated by a shaded symbol. The phenotypes and genotypes...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
a. Determine the most probable mode of inheritance: autosomal or sex-linked, dominant or recessive, of the...
a. Determine the most probable mode of inheritance: autosomal or sex-linked, dominant or recessive, of the disorders in the two pedigrees shown below and indicate the genotypes of as many individuals as possible. 0 0 | ●ㅇ 이 vod 0d b. If individual IV-1 from the first pedigree marries an affected woman, what is the probability that their first child is affected by the disorder? c. If individual IV-3 from the second pedigree marries a normal man, what is the...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance:...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at once among several members of one generation (siblings) *** Autosomal dominant inheritance each affected individual has an affected parent -when one parent is affected, transmission to the offspring (on average) *** -two unaffected parents do not transmit...
What is the mode of inheritance for hypercholesterolemia? a. Autosomal dominant b. Autosomal recessive c. X-linked...
What is the mode of inheritance for hypercholesterolemia?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible
----------------------------------------------------------------
What is the mode of inheritance for Hunter's syndrome?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible.
------------------------------------------------------------
What is the genotype for individual II-3 at the
hypercholesterolemia locus (dominant allele is denoted by H,
recessive allele...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
Web Genotypes and phenotypes for some common single gene inheritance patterns. Inheritance Pattern Genotype Phenotype Affected Affected Not affected AA Autosomal Dominant Aa aa NN Not affected Not affected Affected Autosomal Recessive Nn nn XXN XNX Normal female Normal female Affected female Normal male Affected male Sex-linked Recessive X"X xNY X"Y Pedigree Analys is Instructions: 1. Examine the following three pedigrees. 2. Determine the most probable pattern of inheritance for each pedigree and record it in the space provided at...
. O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree charts on the following page, determine which pattern of inheritance most likely explains the observed pattern of traits in the family shown. Observe the general patterns in the pedigree charts on the following page o males vs females? parents with disease? Compare these patterns with the clues on the previous page to hypothesize a pattern of inheritance Based on this pattern of inheritance, use...
Review This pedigree shows the inheritance pattern of a recessive maternal effect gene in Drosophila. In maternal effect, the offspring's phenotype is under the control of nuclear gene products present in the mother's egg. In this example, the presence of the at allele in the mother is required for proper wing development in the offspring. Submit Previous Answers Correct In the pedigree, individuals who are wingless are indicated by a shaded symbol. The phenotypes and genotypes are only provided for...
PEDIGREES When a trait follows Mendelian inheritance it is often possible to figure out its dominance state by using a pedigree. Below are four pedigrees for four different traits. They are all autosomal traits (meaning they are not inherited on the X or Y chromosomes). For each trait, determine if it is dominant, recessive or unable to be determined. And explain each answer If it helps your explanation, you may label the symbols with letters Remember squares are males, circles...
II Review a tla + This pedigree shows the inheritance pattern of a recessive maternal effect gene in Drosophila. In maternal effect, the offspring's phenotype is under the control of nuclear gene products present in the mother's egg. In this example, the presence of the a + allele in the mother is required for proper wing development in the offspring. a tla a/a In the pedigree, individuals who are wingless are indicated by a shaded symbol. The phenotypes and genotypes...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
a. Determine the most probable mode of inheritance: autosomal or sex-linked, dominant or recessive, of the disorders in the two pedigrees shown below and indicate the genotypes of as many individuals as possible. 0 0 | ●ㅇ 이 vod 0d b. If individual IV-1 from the first pedigree marries an affected woman, what is the probability that their first child is affected by the disorder? c. If individual IV-3 from the second pedigree marries a normal man, what is the...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at once among several members of one generation (siblings) *** Autosomal dominant inheritance each affected individual has an affected parent -when one parent is affected, transmission to the offspring (on average) *** -two unaffected parents do not transmit...
What is the mode of inheritance for hypercholesterolemia?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible
----------------------------------------------------------------
What is the mode of inheritance for Hunter's syndrome?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible.
------------------------------------------------------------
What is the genotype for individual II-3 at the
hypercholesterolemia locus (dominant allele is denoted by H,
recessive allele...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
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