Question

Text Direction に] Align Text Convert to SmatArtArange Styl Paragraph Drawing The Best Medicine? As a prelude to nursing school, you've been volunteering with Dr. Rousseau this semester to pick up valuable experience. She's just finished the examination of two patients who complains of tightness in the chest, extreme difficulty in breathing, a deep cough, and a fever-she tells you these are all classic symptoms of pneumonia. x-rays confirm that the patients are both suffering fronm pneumonia. Dr. Rousseau has also requested a Gram stairn of the each patient's sputum sample- review the staining results on the next slides!)

Please use the first three pictures to help me answer 3,4,5 thank u

Answer 1

3) The micro-organism responsible for pneumonia in patient #1 is Legionella pneumophila. It is a rod shaped gram negative bacilli and belongs to domain bacteria, phylum protobacteria, class gammaprotobacteria, and family legionellaceae

In patient #2, pneumonia is caused by Streptococcus Pneumoniae. It is a  gram positive bacteria usually found in pairs of cocci or diplococci, ocurring singly or in the form of chains. it also belong to domain - bacteria.

4) Penicillin will not be effective in the treatment of Legionella infection, because penicillin is mostly active against gram positive bacteria. As indicated earlier, Legionella pneumophila is a gram negative bacteria and are susceptible to macrolide antibuiotics (azithromycin) and quinolones(like ciprofloxacin).

Penicillin is the drug of choice for the treatment of Streptococcal pneumonia despite prevalence of  resistant pnuemococcal strains. Whether penicillin will be highly effective or not depends upon the susceptibility of Streptococcal strain involved. If strain is highly susceptible penicillin will be highly effective in these patients with adequate doses.

5) rRNA-A site ( rRNA- aminoacyl t-RNA site) is a major target for various antibiotics like aminoglycosides. Because prokaryotic cell (bacteria) contains 16S rRNA and human have 18S , therefore these antibiotics selectively kill bacteria. Binding of drug to 16S subunit at the aminoacyl site(A-site) of 30S subunit of ribosomes leads to decrease in translational accuracy and inhibition of translation of ribosomes. so enlogation is also inhibited so erroneous proteins are synthesized which cause bacterial death.