Question

How cancer work! In this case, we have "thyroid cancer", using the provided words and sentences to draw a concept map linking fine needle aspirate, local DNA inversion,NTRK1, radioiodine, TPM3, thyroid cancer, thyroidectomy, Trk, ultrasound.

Please provide the explanation. Thanks

Answer 1

or Tyrosine Kenese receptor [No 2 These TRK protein / geve is enseded by NT Rk 1 ges! TRK oneogenes are common in papillary thyroid cancer (PTC) hese genes/Protein arise from 3 terminal sequence of NTRKI receptor gune or 5't Thes Segnancy TPM3 NTRKI = Neut Neurotrophic tyrosine kinace Receptor Type 1 TPM3 = Tropomysin alpha- 3 These gaires are drivers of oneogenes gene.

NO 1 Thyroid nodule Fine needle aspiration done histological diagnosis or cytological evaluation For (Iodine radioisotopes or radio iodine. 133T Ca be also used to diagnose e treatment Thywid Careers may originate from mutations of a a variety of genetic allerations are seen here Some are specific genes associated T Thy. Caner. DTRK - It is a gene & the taga (Receptor Tyrosine ki Tyrosine kinase receptor or

N05 1st do INA todent, the froid redula Good for Pre Weation (papillang Begunda diagnosis on not to chone by 1st one of Go for and fun which should see ultrasound guidad FNAC which easily point out nodules and sampling will lee easie, And Last o all All differentiated not anaplastic Ingrond camers should be treated leg removal of thy widectory, hyroidectony may be almost total of obectony depending on the stage of the discuss

Well differentiated Thyroid Cancer 0 Radio iodine Treatment can be given Because it can mildly incorporate radio iodine, should be done with Surgical intervention. weeks post operature breatment with QENA is the 1st step in evaluation of thyroid MA

NO3 Mutation in Thyroid cancer pasti mble in Anadlestic hynid lancer or (ATC) occur in gene INNB1 which encodes Beta Caterin, responsible for ANA rpaix, apoptosis ete. So y defect news there and local DNA niversion ete oceus due to mutation ATC.