19. Salicylic acid, CeH,OHCOOH, is used in the manufacture of acetylsalicylic acid (aspirin) and methyl salicylate...
Experiment 10: Synthesis of Aspirin Name: Data/observations: Day 1Preparation of Salicylic Acid 1.1749 mass of methyl salicylate (wintergreen oil) 0.913 g mass of salicylic acid product Day 2: Synthesis of Aspirin 0.889 mass of salicyclic acid used to synthesize aspirin 0.622 g mass of aspirin product Day 3: Qualitative Analysis Compound pure pure aspirin salicylic acid aspirin pure salicyclic methyl acid product product salicylate purple w/ dark purple night yellow dark purple yeilow seperation crystalized crystalized watery Chunky. FeCl3 Observation...
Mass of salicylic acid recovered= 11.495g Used 1.410g of salicylic acid when synthesizing aspirin. Mass of acetylsalicylic acid(aspirin) recovered= 2.365g Discuss your yields, % yield of salicylic acid and aspirin. The reaction is the synthesis of salicylic acid from oil wintergreen, and then using the salicylic acid to synthesize aspirin. THANK YOU IN ADVANCE
75. Salicylic acid, HOC6H4CO2H, and its derivatives have been used as pain relievers for a long time. Salicylic acid occurs in small amounts in the leaves, bark, and roots of some vegetation (most notably historically in the bark of the willow tree). Extracts of these plants have been used as medications for centuries. The acid was first isolated in the laboratory in 1838. (a) Both functional groups of salicylic acid ionize in water, with Ka = 1.0 × 10−3 for...
A typical aspirin tablet contains 324 mg of acetylsalicylic acid (C9H8O4), a monoprotic acid having a Ka = 3.0 x 10-4. If you dissolve two aspirin tablets in 300. mL of water, what is the pH of the solution acetylsalicylic acid? A typical aspirin tablet contains 324 mg of acetylsalicylic acid (C9H8O4), a monoprotic acid having a Ka = 3.0 x 10-4. If you dissolve two aspirin tablets in 300. mL of water, what is the percent dissociation of the...
PREPARATION OF PHARMACEUTICALS - Fischer Esterification Reactions Q: Calculate the expected mass of both methyl salicylate and aspirin assuming 100% yield. EXPERIMENT7 PREPARATION OF PHARMACEUTICALS Fischer Esterification Reactions Almost 2500 years ago, physicians such as Hippocrates recommended that patients chew on the bark of the willow to alleviate pain. The active ingredient in willow bark was found to be salicin, a compound made of a molecule of salicyl alcohol bonded to a p-D-glucose molecule. In the stomach, the bond between...
Aspirin (acetylsalicylic acid, C9H8O4) is a weak monoprotic acid. To determine its acid-dissociation constant, a student dissolved 2.00 g of aspirin in 0.600 L of water and measured the pH. What was the Ka value calculated by the student if the pH of the solution was 2.62?
I compounds are aspirin (acetyl salicylic acid) and methyl salicylate (i.e. alcohols, aldehydes, ketones, acids, esters, amides, etc)? 5. Describe what physiological effects aspirin causes in the body, eg. regarding body temperature, pain, swelling and thrombosis (blood clotting). Does it inhibit an enzyme? If so, what enzyme does it inhibit and what substances are formed by that enzyme? [You should check the text book for information on aspirin's actions]. 6. Aspirin belongs to a specific class of drugs known as...
1.0.980 g of acetylsalicylic acid was obtained from 1.00 g of salicylic acid by reaction with excess acetic anhydride. Calculate the percent yield of acetylsalicylic acid. 2. Two esters with the empirical formula C3H602 may be prepared. Write structural formulas for these esters and name them 3. How would you prepare the two esters in question 2? Draw a reaction for each. 1. Explain why you would or would not expect to observe a color change if FeClj were to...
Aspirin (acetylsalicylic acid, HC9H2O4) has a value of Ka equal to 3.3x10^-4. What is the pH after 652 mg of aspirin is dissolved in a solution of 237 mL? Set up an ICE table in order to determine the unknown, set up the expression for Ka in order to determine the unknown, and then determine the pH of the solution.
The active ingredient in aspirin is acetylsalicylic acid (HC9H704), a monoprotic acid with a Ka of 3.3 x 10-4 at 25°C. Part A You may want to reference (Pages 680 - 690) Section 16.6 while completing this problem. What is the pH of a solution obtained by dissolving two extra-strength aspirin tablets, containing 410 mg of acetylsalicylic acid each, in 270 mL of water? Express your answer to two decimal places. V AED o 2 ? pH = pH= Submit