2. Draw mechanisms for the following reactions (a. 3 points, b. 2 points). a) من ΕΙΟ,...
(27 points) Draw “arrow pushing” mechanisms for THREE of the reactions in question 1 1) (27 points) Provide the missing reactants, reagents or products 1) NaBH4 2) H30+ H30+ H =- Nat COH H2N. NH2NH2, KOH & www.ro 1) onto ✓ I H 2) H30+ Croz H2SO4 HO H20 1) Mg, EtOEt 2) D. wa PH 3) H30+
Determine the missing products or reagents. Draw arrow pushing mechanisms for 3 of the above reactions. 1) (27 points) Provide the missing reactants, reagents or products 1) NaBH4 2) H30+ H30* H-= - Nat CO2H HON H+ muly & West NH NH2, KOH 1) PP / H 2) H30+ Croz H2SO4 HO H20 1) Mg, EtOEt OH 3) H30+
3. (3x10 = 30 points) Reactions. Give major product structure of following reactions. Indicates stereochemistry where appropriate. i. NaOEt EtO A) ii. H20* i. MeMgBr (excess) OMe ii. H2O AIBr3 i.NaH ii. Et! Ph3P=CHCH3
3) Write the mechanisms leading to the formation of the given ester for reactions A and B.Based on the mechanism, draw the stereochemistry of the starred carbon for each reaction. Briefly comment on how your mechanism corroborates your stereochemical assignment for each reaction. (D = deuterium) 1. NaOH оно o Ph OH - Ph. - Ph Comment: LUULUUL1111111111144444 O HD Phosph PhOH Comment:
1. Name the following or Draw the Structure (2 x 3 pts each) a. N-methyl-3-phenylpentan-2-amine OH b. OH NH2O 2. Draw the starting materials for the following hydrolysis reactions. (3 pts each) 1. NaOH, H2O a. 3-or 2. HCI, H2O OH OH Ph 1. NaOH, H2O b. HO Н. CH3 OH HPh 2. HCI, H2O 3. Of the following, which form would actually exist at: (5 points) a) pH = 2 (acidic) b) pH = 7 (neutral) c) pH =...
Draw the reaction mechanisms of the following reactions: a) Adipic acid with NaOH b) Adipic Acid with Sodium Bicarbonate c) Adpic Acid with HCl
4. Synthesis Reactions. Draw the feature product of the following reactions. (8 x 3 pts) 1. Mg Ph Br 2. CO2 3. H a "NH2 Ph 1. NaOH, CI 2. LAIH b. CHỊCH NHA NaBHgCN, H+ Ph C. Br (excess) NH d NaOH H HO OH H CH e. 1. NaOH H2O NH 2. H+ o= 1. NaOH H2O 2. SOCI N(CH3)2 3 HO
Draw the products formed in the reactions below: 1) LDA 2) 3) H20 NaOCH3 b CH3OH, heat oo OEt с + N EtOH NH3, H20 d 요 NaBH3CH pH=2-3 1)KOH NH CI 2) 3) OH, H20 NaNO3 NH HCI
1. Give stepwise mechanisms for the following reactions. Clearly show all intermediates and use arrows to show electron movement. - Hop Wow Peonic plure H-Br RO-OR, heat I Br b. R oh solla Red + S02 + Hl- c. Al cu. -CH = CH –O-CH3 Hbg, 4pH OH + HCl. 0 KOEI 1. Nat o Et, Etoh il I 10, EL + C CH₂ OH 2. Hoot TOE 1.HCl, H₂O 2. Et3N, Eto ce U
Draw the structure of the major organic product of these reactions. Do not write mechanisms. НО. (h) OH + NADH two organic products; write both NH NHA KOH (i) H H20 heat N 1 H (1) O= 오 HT CH3 H, C12H160 (i) (2) PhCH CH Br (3) H20*