In this reaction ketone group is converted to enolate with LDA then aldehyde is react with enolate they given final product
1) Lithium Diisopropyl amide (LDA) 2) CH3Br
(3 pts) Lithium diisopropyl amide (LDA) could theoretically act as a nucleophile or a base. With that in mind, draw the four theoretical products (3 from E2 and 1 from SN2) of the reaction below. Then, circle the major product. Provide a brief rationale. 2. Br N Li
2. Starting from CH CH.Br and diisopropyl amine, describe how you would prepare lithium diisopropyl amide (LDA), LINR, where R=Isopropyl. (5 points) 3. Write the products of the reactions below. (20 points). add to LDA -78 work up with HCI work up with HCI
please help 2. 3 pts) Lithium disopropyl amide (LDA) could theoretically act as a nucleophile or a base. With that in mind, draw the four theoretical products (3 from E2 and 1 from S,2) of the reaction below. Then, circle the major product. Provide a brief rationale. Br
could someone please help me out in organic chemistry? Last Name- - First Same 1. Write the products of the following reactions. If there is no reaction write NR (30 points). a) CHCH.CH-Br + 2Li => "X" +LiBr: X=? C) 2 "X" + Cul Lil + "Y": Y- S and water d) (U) Y + 2. Starting from CH CH Br and diisopropyl amine, describe how you would prepare lithium diisopropy! amide (LDA), LINR, where R=Isopropyl (5 points) 2. Starting...
2. Wildt reagents are mixed to make LDA? Remember that bonds to lithium are lonic. e, not a.-d.
8. LDA, lithium diisopropylamide functions as a(n): A. strong kinetic base C. electrophilic nitrogen reagent B. strong nucleophile D. weak lithium orgaometallic agent
2-Methylcyclopentanone treated with lithium diisopropylamide (LDA) followed by addition of formaldehyde results in a crossed aldol reaction. OH (1) LDA (2) 4,0 Complete the mechanism for the reaction by adding missing curved arrows, atoms, bonds, charges and nonbonding electrons. introduced the aldehyde 0: с + NH(Pr)2 Но сна Сн, ен, GH енен, Water added in workup step. өн H3C НЭС final product NOY
What is the major organic product expected from the reaction of 3,5-dimethylcyclohexanone with LDA (lithium diisopropylamide) followed by methyl iodide? Select one: a. 3,3,5-trimethylcyclohexanone b. methanol c. 2,3,5-trimethylcyclopentanone d. 2,3,5-trimethylcyclohexanone e. 2,3,5-trimethylcyclohexanol
5. Lithium bis(trimethylsilyl)amide (LIHMDS) is a common base in organic synthesis. Please predict the major and minor products from the reaction with compound 1. Then, sketch a reaction energy diagram showing formation of products A (major) and B (minor). (8 pts) (LIHMDS) THE major (product A) minor (product B) Energy rxn