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A 2-year-old boy is sent for immunologic testing because of recurring respiratory infections, including several bouts...

A 2-year-old boy is sent for immunologic testing because of recurring respiratory infections, including several bouts of pneumonia. The results show decreased immunoglobulin levels, especially IgG. Although his white blood cell count was within the normal range, the lymphocyte count was low. Flow Cytometry (cellular separation based on size and CD markers) was performed to determine if a particular subset of lymphocytes was low or missing. It was determined that he had a low number of CD3+ lymphocytes, although the CD19+ lymphocyte population was normal. How can this be interpreted? In other words explain the roles of the cell populations described, how the decrease or normal level of each affects the function of the patient’s immune system. How does this support or relate specifically to the patients recurring bacterial infection?

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