the most likely impurity in aspirin synthesis is the presence of some unreacted starting material, salicylic...
the most likely impurity in aspirin synthesis is the presence of some unreacted starting material, salicylic acid. what effect might there be on a person who ingested aspirin tablets containing this impurity
Homework Answers
Salicylic acid can cause allergic reaction or skin irritation. So, a person who ingested aspirin tablets containing salicylic acid as impurity can feel the following effects:
1. Headache and problem with hearing
2. Stomach pain and vomiting
3. Rash in skin
Add Answer to:
the most likely impurity in aspirin synthesis is the presence of
some unreacted starting material, salicylic...
need help on 1,2,3,4 1. The starting material for aspirin is salicylic acid which is a...
need help on 1,2,3,4
1. The starting material for aspirin is salicylic acid which is a phenol. • (2 pts) Which chemical test will you use to test for unreacted phenol when the aspirin synthesis is completed? (It's a chemical test you have used earlier in the semester) (2 pts) What does a positive test for phenol look like using this test? 2. When finding a melting point experimentally, it is always reported as a range T1-T2. 2a. (3 pts)...
10. Calculate the theoretical yield of aspirin using 4.00 g of salicylic acid as the starting...
10. Calculate the theoretical yield of aspirin using 4.00 g of salicylic acid as the starting material. Assume acetic anhydride is in excess. (Hint: from the mass of salicylic acid acid use, how many moles of salycilic acid are present intitially? What is the salycilic acid : acetylsalicylic acid molar ratio? How many moles of acetylsalicylic acid are formed assuming 100% yield? Based on this abount of moles, how many grams of acetylsalicylic acid are formed? (this is the theoretical...
QUESTION 3 Salicylic acid reacts with acetic anhydride to form aspirin and acetic acid as shown. Use the equation to answer Questions 3 – 6. (salicylic acid) ...
QUESTION 3 Salicylic acid reacts with acetic anhydride to form aspirin and acetic acid as shown. Use the equation to answer Questions 3 – 6. (salicylic acid) (aspirin) C7H6O3 (s) + C4H6O3 (l) → C9H8O4 (s) + CH3COOH (l) MM = 138 MM = 180 If we divide 180 by 138 we find that 1.00 g salicylic acid will produce a maximum of 1.30 g aspirin. 3. A student starts with 3.20 g salicylic acid. What is the maximum amount...
:**(((PLEASE HELP ASAP NEED IT TODAY! THANK YOU IN ADVANCE! 13.46 Chemists have developed several syntheses for the antiasthmatic drug albuterol (Proventil). One of these syntheses starts with salicylic acid, the same acid that is the starting material fo
13.46 Chemists have developed several syntheses for the antiasthmatic drug albuterol (Proventil). One of these syntheses starts with salicylic acid, the same acid that is the starting material for the synthesis of aspirin: JUST A,C,D,E,F
W cepted. Please do not ask for special treatment. 1. The starting material for aspirin is...
W cepted. Please do not ask for special treatment. 1. The starting material for aspirin is salicylic acid which is a phenol • 2 pts) Which chemical test will you use to test for unrearted phenol when the aspirin sync (it's a chemical test you have used earlier in the semester) cted phenol when the aspirin synthesis is completed? • (2 pts) What does a positive test for phenol look like using this test? 2. When finding a melting point...
7. You think organic synthesis is a headache? Why not make some aspirin? Starting from phenol, ho...
7. You think organic synthesis is a headache? Why not make some aspirin? Starting from phenol, how would synthesize the product with the given list of chemicals below. (5 pts) There is more than one way to do this. Do worry about specific solvent conditions only reagent conditions you List of reagents: HO Ethanol Methanol Actone HC H,SO, (fuming) H,SO HNO NaOH NH, NaNH Phenol Aspirin Jones Reagent mCPBA NHNH2 SOC LiAIH Zn Hg Pyridine TMSC NaBH Lindlars Catalyst Pd...
please help Mustrates treat all types of ilnesses. Background Aspirin is a prodrug of salicylic acid,...
please help
Mustrates treat all types of ilnesses. Background Aspirin is a prodrug of salicylic acid, the actual active drug. A compound related to salicylic acid, salicin, was first isolated from willow bark in the mid 1700's, but willow-bark extract was used by the andient Greeks as a treatment for pain and fever. Salicylic acid (and many related phenols) are very hard on your Ho stomach, but when esterified, as aspirin is, they are much better tolerated. Simple esters are...
Pre-lab Questions: Importance A one-step preparation of aspirin from its precursor, salicylic acid, via an ester...
Pre-lab Questions:
Importance A one-step preparation of aspirin from its precursor, salicylic acid, via an ester formation illustrates one of synthetic organic chemistry's most important uses, making the drugs that treat all types of illnesses. OH HOOH Background Aspirin is a prodrug of salicylic acid, the actual active drug. A compound related to salicylic acid, salicin, was first isolated from willow bark in the mid 1700's, but willow-bark extract was used by the ancient Greeks as a treatment for pain...
Devise the most efficient synthesis for the carboxylic acid below using a starting material and reagents...
Devise the most efficient synthesis for the carboxylic acid below using a starting material and reagents from the tables. Give route by specifying the number of the starting material followed by the letters of the reagents you would use beginning with the step. Reagents a Mg/dry ether b 1. CO_2 2. acidic workup c NaCN/The or DMF d NaCN/dil. aqueous H_2SO_4 e Aqueous H_2SO_4 at reflux f Conc, HCl or HCl (gas) g PBr_3 h KOH/alcohol i KMnO_4/H_3 O^+ j...
Devise the most efficient synthesis for the carboxylic acid below using a starting material and reagents...
Devise the most efficient synthesis for the carboxylic acid below using a starting material and reagents from the tables. Give your route by specifying the number of the starting material followed by the letters of the reagents you would use beginning with the first step. The answer 4fh means treat t-butanol(4) with conc. HCl(f) then treat the product with KOH in alcohol(h). Mg/dry ether CO_2 acidic workup NaCN/THF or DMF NaCN/dil. Aqueous H_2SO_4 Ethanol, H_2SO_4 [trace) at reflux Conc. HCl...
need help on 1,2,3,4
1. The starting material for aspirin is salicylic acid which is a phenol. • (2 pts) Which chemical test will you use to test for unreacted phenol when the aspirin synthesis is completed? (It's a chemical test you have used earlier in the semester) (2 pts) What does a positive test for phenol look like using this test? 2. When finding a melting point experimentally, it is always reported as a range T1-T2. 2a. (3 pts)...
10. Calculate the theoretical yield of aspirin using 4.00 g of salicylic acid as the starting material. Assume acetic anhydride is in excess. (Hint: from the mass of salicylic acid acid use, how many moles of salycilic acid are present intitially? What is the salycilic acid : acetylsalicylic acid molar ratio? How many moles of acetylsalicylic acid are formed assuming 100% yield? Based on this abount of moles, how many grams of acetylsalicylic acid are formed? (this is the theoretical...
W cepted. Please do not ask for special treatment. 1. The starting material for aspirin is salicylic acid which is a phenol • 2 pts) Which chemical test will you use to test for unrearted phenol when the aspirin sync (it's a chemical test you have used earlier in the semester) cted phenol when the aspirin synthesis is completed? • (2 pts) What does a positive test for phenol look like using this test? 2. When finding a melting point...
7. You think organic synthesis is a headache? Why not make some aspirin? Starting from phenol, how would synthesize the product with the given list of chemicals below. (5 pts) There is more than one way to do this. Do worry about specific solvent conditions only reagent conditions you List of reagents: HO Ethanol Methanol Actone HC H,SO, (fuming) H,SO HNO NaOH NH, NaNH Phenol Aspirin Jones Reagent mCPBA NHNH2 SOC LiAIH Zn Hg Pyridine TMSC NaBH Lindlars Catalyst Pd...
please help
Mustrates treat all types of ilnesses. Background Aspirin is a prodrug of salicylic acid, the actual active drug. A compound related to salicylic acid, salicin, was first isolated from willow bark in the mid 1700's, but willow-bark extract was used by the andient Greeks as a treatment for pain and fever. Salicylic acid (and many related phenols) are very hard on your Ho stomach, but when esterified, as aspirin is, they are much better tolerated. Simple esters are...
Pre-lab Questions:
Importance A one-step preparation of aspirin from its precursor, salicylic acid, via an ester formation illustrates one of synthetic organic chemistry's most important uses, making the drugs that treat all types of illnesses. OH HOOH Background Aspirin is a prodrug of salicylic acid, the actual active drug. A compound related to salicylic acid, salicin, was first isolated from willow bark in the mid 1700's, but willow-bark extract was used by the ancient Greeks as a treatment for pain...
Devise the most efficient synthesis for the carboxylic acid below using a starting material and reagents from the tables. Give route by specifying the number of the starting material followed by the letters of the reagents you would use beginning with the step. Reagents a Mg/dry ether b 1. CO_2 2. acidic workup c NaCN/The or DMF d NaCN/dil. aqueous H_2SO_4 e Aqueous H_2SO_4 at reflux f Conc, HCl or HCl (gas) g PBr_3 h KOH/alcohol i KMnO_4/H_3 O^+ j...
Devise the most efficient synthesis for the carboxylic acid below using a starting material and reagents from the tables. Give your route by specifying the number of the starting material followed by the letters of the reagents you would use beginning with the first step. The answer 4fh means treat t-butanol(4) with conc. HCl(f) then treat the product with KOH in alcohol(h). Mg/dry ether CO_2 acidic workup NaCN/THF or DMF NaCN/dil. Aqueous H_2SO_4 Ethanol, H_2SO_4 [trace) at reflux Conc. HCl...
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