Question

Help, please.

Which statements are true? Explain why or why not. 24-1 Tcells whose receptors strongly bind a self-pep- tide-MHC complex are killed off in peripheral lymphoid organs when they encounter the self peptide on an anti gen-presenting dendritic cell 24-2 To guarantee that the antigen-presenting cells in the thymus will display a complete repertoire of self pep- tides to allow elimination of self-reactive T cells, the thy mus recruits dendritic cells from all over the body 24-3 The antibody diversity created by the combinato- rial joining of V, D, and J segments by V(D)J recombination pales in comparison to the enormous diversity created by the random gain and loss of nucleotides at V, D, andJ join ing sites.

Answer 1

24-1 T cells whose receptors strongly bind a self- pep- tide MHC complex are killed off in peripheral lymphoid organs when they encounter the self-peptide on an antigen presentation dendritic cell..

T cells development occurs in the thymus..lymphoid progenitors developed from hematopoietic stem cells in the bone marrow migrate to the thymus to complete their antigen_ dependent maturation in to functional T cell ..T-cell antigen recognition inadaptive immunity,it shapes T-cell repertoire in the thymus and directs T cell mediated effector function in the periphery..All cell types can serve as form of Antigen- presenting cell..professional antigen presenting cells are dendritic cell present in Tcell..In addition to the MHC proteins relies in in molecules in APCs and T cells..