Question

please i need a guide on the stepwise mechanisms of the following reactions

Scheme 4.2. (Continued) CH, OR 403 CH,OH, DTBP, 25°C C,H,OH, DTBP 40°C НСОН, ОТВР,0°C SECTION 78. n. 58% . 42% in 13% vet. CF.CH OH DTBP. 25°C I-BUOH, 20% H,0,25°C dioxane, 20% H 0,25°C CHCHCH, 49% inv. 6 CHSCHCH 15% inv. K-OCCHg. CH3COH, 50°C Et,NO,CCHE 50% acetone OCCH CH,CHCH 65% Осан, CH CH, * K-OCCH. Cg H₂CC₂Hs OPNB 5+2% inv. CH,CO2H, 23°C C.H.CCHS ACHẠCH 56 15 in. Nang in CH OH, 65°C C, H, CC2H5 14% in CHE CHECCH OCH CH 38% ret CHECCH 90% aq, acetone -nitroben: DSP- wate:OPMB OBs -toluenesulfonate; OPMB = pain P-bromobenzenesulfo benzenesulfonate: OTs olle, J. Am. Chem. Soc., 87, 3682 (1965) Chem. Soc. 77. 1117 (1955). Walth and Weller Chem. Soc., 87. JOS Am Chem. Soc. 87. 287 (1965). Ch a r Par Tra , 2, 2232 (2000 ell). AmChem Soc. 59, 2536 (1957) 1200/1967).

Answer 1

General Mechanism Lod Nuo SN2 mechanism. NU V The nucleophile will attack from Opposite direction to SNR mechanism. Nao can attack from both side giving rise to mixture af products (a omers) the leaving group to to o inversion af stereochemist The reaction can happen via Sore or sul reaction board depending on oracheophilic attack leading to a mixture of enantiomers ure o que CH, OBLA Sw? Preffend EBUCH Al ethyl group is bultier tham methanol sou2 feaction is less over methanol сган,он s mixture of enantiomere as this is not a strong nucleophile allowing the noolecule to form Same as Cfg ULOH reaction H₂O is a good nucleophile leading to Sw2 pathway giving mixture of Products a carbocation leading to Sul mechanistre pathway