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You have pyelonephritis and, in your particular case, in addition to renal dysfunction, the poor filtration,...

You have pyelonephritis and, in your particular case, in addition to renal dysfunction, the poor filtration, reabsorption, and/or secretion are indirectly causing a number of digestive—and other systemic—problems. 1.

One of the major systemic consequences of this infection is a global shift in the balance of autonomic tone in favour of sympathetic.

Explain the local and systemic physiological consequences of this shift with regard to its influence on each of the following.

1.1. micturition and the gut-brain axis

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Pyelonephritis leads to the spread of infection tto bladder and urethra and cause UTI(uurinary tract infection ) that lead to burning mituration and pain during mituration and incomplete voidenece of the urine at a time ---these are local consequences

Due to disturb in renal function and and as qsn states that there is poor filtration it lead to accumulation of the nitrogen substance and lead to the encephalopathy and disturbance in the consicecnuses

Accumulation of nitrogen in gut by the transformation by bacteria is also not cleared and that also caause serioius problem to the mental status

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