Question

2. (4 pts) Assign (R) or (S) configurations to each of the following compounds. H₃C он Wyo

Answer 1

Chiral centre 611 Hoci Hacirige G₂ ce : Gif (ringl group). G se (estunl group) o & Among the towi group, at is highest priority as all the other groups are connected through Carton atom (e) to the chiral centre, which has low atomic no tuancl... Now, among & the three other groups. are other & H 14 C600) Çooo 1 1 an , Hi af ef ten at It H 4- ait I

. cartons H3 was lowest priority on the connecting Connecwhile Catom stuer is primary one while two, G & G & are se Secondary & G are C000) C600) > He-cf G: H₂C - at Ht 14 It The double can be viewed as, botno the carton is singhy bon to another Carbon

That makes the connecting atom. Carbon a tertiary one and so gets higher priority tham Granto so, the priority order te, a> G, > G > Catz til fwing wedge conformation of the molecule be,

De The lowest prioritised group is. away from our point of view from above the plane of page, 123 is clockwise, so Configuration is .. -CN Yol HO No. -OH has highest priority ( Adonie weight of o is greater than c)..

Between. & CN - 14 a H oo (ooo) en C or, I t -1 Igen o=U Co=o com be interpretadas, cis bonded with two oxygen ondom singly so - (-H & CH₂ CN, on ars, on the the former is carbon is attached to oxygen an it e caton.. the is connected to laterone Conc, atomic No. priority).. and while to oxygen atom

taessa then, order is, o tots tc-H – Cota CNH .. No. W group is awarg and 1 2 3 is anti-clock wise. The configuration is ().. NC (5) 12 A

the Groups are short hand to G, Gz and bez highest prioritised group is, tote-CACH, as the connecting atom is o while rest sturee, have c. GI +- os = + ce - 19 I I 1 carbon, one Carton. attached with сиз CA 3 LN - CH3 G3 @H2 zo (secondary Carbon)

et G2 det it can be intepretated as below (2000) (1000) et Chiral Centre H- C 30, tertiary Carton

We know, priority order, .: 8 30 7 2007 iC; The priority order becomes, i bez > Gg > G the molecule is t o - bond, alo rotating the the molecule 3. No. W group is away and in 2 is anticlock wise, configuration is, (s) so,