Question
  1. Assume that there were 2,035 non-smoking women at the start of follow-up and 350 women smokers. What is the cumulative incidence of CHD mortality per 1000 persons at risk among each of these groups over the follow-up period?
  2. Over the period of the study follow-up, from 1968 – 1984, there were 58 deaths from CHD among women in the study. Were these incident deaths or prevalent deaths? Explain.

TABLE 1. Relative rlsks of coronary heart dlsease (CHD) mortality accordlng to major cardlovascular rlak factore: Flnnlsh Mobllo Clnlc Study, 1988-1984 Men (n - 2,748) Person Relatveconfiance Women (n 2,385) No.of Pei901* Rolatve conidenc No, ol 95% 95% CHO years ๙ cases lolow-up CHD years of Inlervalcases foliow-up dak risk Interval Age (years)t 30-39 40-49 50-59 60-69 1814,943 48 12,560 69 7,677 2 12,627 10 10,972 1.3-26.3 7,63818.5 3.9-70.6 3,86642.6 0.1-179.3 3.21.8-5.5 7,5 4.4-12.5 20 5.8 3,16913.47.8-22.9 28 Smoklng Nonsmoker Current smoker 72 19,090 114 19,259 41 29,827 17 1.8 1.3-2.4 5,114 4.0 2.3-7.2 Body mass index terlle (kg/m2) s24.0 24.1--26.7 >28.7 68 2,585 48 12,925 70 12,823 1311,796 1811,707 27 11,518 0.7 0.5-1.0 0.9 1.0 0,5-1.0 0.6-1.9 Cholesteroi tertile (mgdi) S237 238-280 >280 36 13,079 5712,946 93 12,324 1.40.8-2.2 2.41.7-3.8 15 11,818 11 11,004 32 11,379 0.2-1.1 0.6-1.9 0.5 Hyportensknt Normotensive Borderllne Mild Dellnite 5317,539 113 18,385 986 1,455 1.61.1-2.2 0.6 0.2-2.1 1.01,1-3.4 816,081 3214,040 1,298 3,743 1.90.04.3 2.2 2.1 0.9-5.4 0.6-7.3 Ago adjusted f No adjustment. t Dofnte hypertenslon: systollc blood pressure (SBP) of 170 mmHg an diastolic blood preasuro (DBP) ot 100 mmHg or anthypertensive medicatilon; mld: S0P ol z160 mmHg and DBP ol 295 mmHg, but nol dofnod as dofinite; nomotensve: SBP of <140 mmHg and DBP of «00 mmHg; borderlne: pereons not definod aa doflntoly or mldly hypertongivo or nomotensive

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