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leonard is a 60 yo 95kg 5'9" male with gram negative sepsis. his Scr is 1.3mg/dl...

leonard is a 60 yo 95kg 5'9" male with gram negative sepsis. his Scr is 1.3mg/dl and is stable. the specialist wants to start gentamicin and asks for a loading and maintenance dose recommendations. gentamicin ke,est(1/h)= 0.00293*CrCL+0.018; Vd=0.26L/kg AdjBw; gentamicin is always infused over 30 minutes.

what is leonards adjusted body weight? what is leonards estimated CrCl? what is leonards estimated gentamcininelimination rate constant? whta is leonards loading dose and maintenance dose?

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Answer #1

Given

Age:60 yr

Weight:95kg

Height :5.9 (179.8 or 180cm)

BMI:29.6 ( Obesity)

Ideal body weight :74.2kg

Average body weight: 80 kg

The adjusted body weight:82.5 kg(50+2.3*height over 60 inches)

Estimated creatinine clearance will be 81.20ml/min [140_age×height÷72×Sr.cr]

580 mg per single dose to be administered

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