Immunohematology / Blood bank. I cannot figure out these two antibody panels. Where do I start?
This category is not nursing but I didnt have the option to select medical lab tech or medical lab scientist
These antibody panels are used in blood bank in the medical lab when screening cells are positive.
The table gives data regarding the various tests performed on donor blood samples to evaluate for transfusion reactions. All tests are aimed at recognizing the various antigens in the Blood sample that may lead to a transfusion reaction when infused .
Though the most popular Blood grouping system with the ABO system, it is said that transfusion reactions may occur due to antigens classified under other Blood Grouping Systems such as Rhesus ,MNS , P , Lewis, Lutheran, Kidd, Duffy and Kell. Each of these blood grouping systems takes into account the presence of particular RBC antigens which are then said to positive (if present) and negative (if antigen is absent)
For the transfusion reactions to be minimal / absent , the donor and recipients blood is to be matched .
The First column gives us the serial number in the table and the third column gives us the identification number for the donor blood sample.
The second column gives us the Genotype of Rh locus (Rhesus) in the long arm of Chromosome 1 according to Weiner Terminology. It is possible to often know the Rhesus blood type by knowing the Genotype.
Wiener shorthand designation |
Rh antigens |
R0 | Dce |
R1 | DCe |
R2 | DcE |
Rz | DCE |
r | dce |
r' | dCe |
r" | dcE |
rz | dCE |
Generally Rh positive blood indicates the presence of D antigen in the sample and vice versa. It can be easily seen that Genotype R -> D present and r -> d (D not present ,that is ,its Rh negative blood sample)
The fourth column in the first table gives us two extra data. The presence of Co(b) allele and Kp (Of the Kell System) both of which are rare occurrences and may participate in transfusion reactions.
Co(b) allele belongs to the Colton Antigen System
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Immunohematology / Blood bank. I cannot figure out these two antibody panels. Where do I start?...
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