Question

M.C., a 59-year-old homemaker, lives on a farm with her husband, R.C. Recently she has been experiencing weight loss, night sweats, and a chronic cough. When she is given the purified protein derivative (PPD) test, the result is positive, and a chest x-ray indicates areas of consolidation characteristic of tuberculosis. M.C. is hospitalized, and special precautions are initiated to prevent the spread to others.

1. What is the next step in diagnosing the disease?
The health care provider orders that M.C. be started on a four-drug regimen consisting of isoniazid, rifampin, pyrazinamide, and ethambutol until the final results of testing are back.

2. What is the purpose of the multiple drugs in this order?

3. What needs to be assessed before M.C. begins this medication therapy?
Two weeks later, M.C. is discharged and given a prescription for Rifamate (combination of rifampin and isoniazid). In addition, she is given instructions to take pyridoxine (vitamin B₆).

4. M.C. asks, “Can't I just take my regular multivitamin? Why do I need this one?” What is the nurse's best response?

Answer 1

1, Rapid sputum test for tuberculosis test bacteria that cause tuberculosis. This test finds out drug-resistant strain TB.
2, this multiple drug regimen treats TB disease that causes bacteria and is susceptible. These multiple drugs help prevent the occurrence of tubercle bacilli resistant to others. single drugs cause the development of resistance to that drug for the people. It will be very effective with a combination of antibiotics.
3, Monitor liver enzymes as a pretreatment. liver disorder and drug-induced liver injury should be monitored before starting medication therapy. because antituberculosis medicines cause liver damage.
4, Vitamin B6(pyridoxine) supplements with isoniazid therapy help prevent peripheral neuropathy when the patient is at high risk. pyridoxine plays an important role in the metabolism of protein, fats, carbohydrate, brain enzymes because isoniazid prevents metabolism function and causes isoniazid induced neuropathy. other multivitamins supplements cause along with this medication cause drug to drug interaction and produce more side effects. stop taking other multivitamins while taking this medication.