Question

Diagnosed with the VDRL and RPR tests, PW is being retreated for multişle sexual transmitled infections (sis), Chianydia and syphilis, and pevic inflammatory disease. She has an allergy to penicilin. 1. What is the rationale for using tetracycline for P.W's STIs? Answer and Rational: 2 What would the nurse teach P W about treatment of a recurrenk infection? Answer and Rational:

Answer 1

a. ANS: Tetracycline using for P.W.’s STIs:

Answer: Syphilis was a systemic disease and it was caused by Treponema pallidum,. Tetracyclines are useful in the treatment of spirochetal infections, as with syphilis and pelvic inflammatory disease.

Rationale: In the susceptible bacteria the drug tetracycline can inhibits the protein synthesis and it can simultaneously inhibits the growth of the pathogen or kills. Gram positive and gram negative bacteria’s like Mycoplasma, Chlamydia and Rickettsia was highly affected by using the drug tetracycline. Regimens of doxycycline and tetracycline have been used in treatment for those allergic to penicillin. Compliance is likely to be better with doxycycline than tetracycline because tetracycline can cause GI side effects and requires more frequent dosing.

b. ANS: Nurse teaching about treatment of a recurrent infection:

Answer: She needs to avoid sexual activity and pregnancy while taking tetracycline. Her sexual partners need to be tested and treated. She should also be tested for other STIs, including HIV infection.

Rationale: Generally several physicians did not suggest during the period of pregnancy because the fetuses was highly affected. So until the complete healing of syphilis sores J.W. should abstain from sexual activity and the serologic tests should be repeated at 6, 12, and 24 months, and her cerebrospinal fluid should be checked tor neurosyphilis. If this neurosyphilis is present, different protocol of treatment must be used.

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