Question

. How to do you know that methotrexate has reached its desired effect?

what is methotrexate Contraindication

Answer 1

Ans) 4-8 weeks
Like all DMARDs, Methotrexate takes time to work. Most patients start to feel the positive effects of methotrexate at 4-8 weeks, with maximum benefit at 3-6 months. Side effects can occur earlier.

- Methotrexate contraindication:

Use is contraindicated in patients with psoriasis or rheumatoid arthritis with alcoholism, alcoholic hepatic disease, or other chronic hepatic disease; further, methotrexate should be given cautiously to any patient with a personal or family history of hepatic disease or significant exposure to liver toxins.