The RANK Ligand is secreted by Osteoclasts (1 point): a. True b. False 21. Bisphosphonates (1...
The RANK Ligand is secreted by Osteoclasts (1 point): a. True b. False 21. Bisphosphonates (1 point): a. Increase the activity of osteoblasts b. Decrease the activity of osteoclasts 22. Which of these drugs is anabolic? (1 point): a. Teriparatide b. Denosumab 23. What is the role of Leptin in a normal subject? (1 point): a. Increases appetite b. Decreases appetite
Homework Answers
1)False.
RANKL ligand is secreted by osteoblasts but not osteoclast.
Osteoblasts form new bone where as osteoclast are bone reobserving cells.The RANK ligand which is secreted by osteoblasts binds to RANK receptor of osteoclast.
2)B.
Decreases the activity of osteoclasts.
The bisphosphonates inhibits the osteoclast activity.It is done by decreasing progenitor development and promoting apoptosis of osteoclasts.
3)Option A.
Teriparatide.
Teriparatide is an anobolic drug.
4) Decreases appetite.
Leptin is a hormone which decreases appetite.
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The RANK Ligand is secreted by Osteoclasts (1 point): a. True b.
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