9) (marks = 3) Provide a reasonable multistep synthesis of the following molecule from the indicated...
Provide a reasonable multistep synthesis of the following molecule from the indicated starting material, using any reagents necessary. (Please include the product and reagents of each individual step in your synthesis. DER
Part IV - Multistep Synthesis [14 marks] A. Propose a synthesis of compound A starting from dimethyl malonate. When choosing your synthetic steps, you can use any hydrocarbon with three or fewer carbon atoms, any solvents or inorganic reagents, and any organic reagents that do not contribute carbon atoms to the carbon skeleton in the product. Clearly show the required reagents and the product of each step. You do not need to show mechanistic (curved) arrows. [6 marks] Dimethyl malonate...
1. Provide a complete retrosynthesis and forward synthesis of the target molecule below from the given starting materials. All carbons of the target must be from the given starting materials. You may use any reagents you find necessary. You may include more than one step over a reaction arrow, but please no more than 3 steps at a time. Please show the key intermediates in your synthesis for partial credit. (10 bonus points) For full credit, include a retrosynthetic analysis,...
please show all steps with necessary mechanism arrows 1. Provide the starting specific nucleophile and electrophile that would result in each of the following molecules using an SN2 reaction. Do consider the ABC and provide the specific reagent necessary. (2 points) Me HH MeMe Me I wyn Me Me 2. Provide a detailed retrosynthesis and synthesis of the following compound from the indicated starting material. All atoms of the target must come from the indicated starting materials. You may use...
2. Devise a multistep synthesis of the target molecule from the starting material shown. Show the reagents needed for each step and the product of each step. Do not show any mechanisms.
Chem 231, Assignment 5 page 6 of 5 Part IV - Multistep Synthesis [14 marks] A. Propose a synthesis of compound A starting from dimethyl malonate. When choosing your synthetic steps, you can use any hydrocarbon with three or fewer carbon atoms, any solvents or inorganic reagents, and any organic reagents that do not contribute carbon atoms to the carbon skeleton in the product. Clearly show the required reagents and the product of each step. You do not need to...
Provide multistep synthesis for the following target molecule from the indicated starting materials NH2 from 0 from NO2 Br
Provide a multistep synthesis for the desired product using the indicated starting material. You may use any additional reagents you wish, but all carbons in the starting material must end up in the product. Do not draw any curved-arrow mechanisms. The best answer will require seven or fewer steps. Starting Material ou (+/-) Desired Product
Provide a multistep synthesis for the desired product using the indicated starting material. You may use any additional reagents you wish, but all carbons the starting material must end up in the product Do not draw any curved-arrow mechanisms. The best answer will require nine or fewer steps. H Starting Material (+/-) Desired Product
1. Consider the following molecule (12 marks total) i. Provide the reaction conditions, and major product, for the monobromination of this molecule (2 marks) ii. Provide the full arrow pushing mechanism for the formation of the major product (making sure to include all initiation, and propagation steps as well as one termination step) (4 marks) (Continuation of Question 1) iii. Provide an explanation for why only one product is obtained through monobromination of this molecule (2 marks) iv. When reacting...