Question

True (a) -False (b) 43. An attribute of adaptive immunity is that it is a specific response toward a pathogen rather than generalized. 44. Self-tolerance is important, otherwise our immune systems would destroy us. 45. The MHCs are capable of presenting intracellular and extracellular antigens. 46. Super antigens are not processed or presented by T helper cells. th hi C 47. B cells directly produce antibodies. 48. Graft vs. host disease is a form of an autoimmune type IV hypersensitivity. 49. Currently, there are no cures or preventions for autoimmune disorders. 50. An allergen is any antigen that triggers IgE production.

Answer 1

43. True - An attribute of adaptive immunity is that it is a specific response toward a pathogen rather than generalized . Five attributes of adaptive immunity: specificity, inducibility, clonality, unresponsiveness to self, and memory

44. True - Self - tolerance is important ,otherwise our immune systems would destroy us . Non-self proteins and cells include infected body cells, cancer cells, cells from other people, and invading organisma. Recognizing self versus non-self, which is necessary to prevent healthy body cells from being destroyed along with the invaders.

45. True - The MHC's are capable of presenting intracellular and extracellular antigens . Extracellular antigen is presented by MHC class || and cytosolic (intracellular antigen) is presented by MHC class |

46. False - Super antigens are not processed or presented by T helper cells . A superantigen is an antigen that can bind independently to Class II MHCs and TCR, away from the variable regions. This leads to stimulation of a large number of T-cells, massive production of cytokines, and systemic toxicity.