Question

Adaptive Immunity questions

1. In which scanario is the Fragment Crystallizable (Fc) potion not needed?

a. Oposonization

b. Adaptive Dependent Cell cytotoxicity

c. Neutralization

d. Antibody activation of C1q

2. Which antibody istotope binds with the highest avidity?

a. IgM

b. IgE

c. IgA

d. IgG

e. IgD

3. Which part of the antibody enables binding to repeated epitopes of variable distance?

a. constant region

b. light chain

c. heavy chain

d. hinge

e. none of the above

4. Antibodies:

a. recognize conformation

b. bind MHC

c. are produced by T-cells

d. are the secreted form of the bcr

e. A and D

5. Antigen-antibody interactions can occur in the:

a. Fc region

b. Fab

c. Variable domains

d. Constant domains

e. B and C

6. Which statement is true?

a. IgM has the highest affinity for antigen of all isotypes because it possesses the highest valency number

b. IgG is the most abundant isotype of any antibody

c. An antibody has 4 light chains and 4 heavy chains

d. Hydrogen bonding does not influence the ability for antibodies to bind antigens

e. hypervariable regions are present at the C terminus of variable domains

Answer 1

Question:

1. In which scanario is the Fragment Crystallizable (Fc) potion not needed?

a. Oposonization

b. Adaptive Dependent Cell cytotoxicity

c. Neutralization

d. Antibody activation of C1q

Solution : c. Neutralization

Neutralisation is the process specific antibodies binds antigens to block pathogenic viruses and Fragment Crystallizable portion is not needed

Opsonization is the process for the destruction of bacteria.Without the opsonization process the recognition and destruction of bacteria would not be possible. in opsonziation IgG antibodies bind to the ibacterium, the binding is in a way. antibody shaped 'Y"The binding of IgG to the bacterium is through "Y."The Fc region is recognized by a receptor on an immune cell called a phagocyte.

Fc in  Adaptive Dependent Cell cytotoxicity

Effector cell Target cell Y Cytotoxic granule Fc-receptor Free antibody Antibody bound to surface antigen

Antibody activation of C1q

IgG antibody can group at the cell surface into hexamers through Fragment Crystallizable, which gives complement component C1q and gives activation.