Question

.11 Sprint 8:56 PM Discussion Forum 7 Soriano S., Alonso-Magdalena P., Garcia- Arevalo M., Novials A., & Muhammed S J. (2012). Rapid insulinotropic action of low doses of Bisphenol-A on mouse and human islets of langerhans: Role of estrogen receptor b. PLoS ONE 7(2) e31109. doi:10.1371/journal.pone. 0031109 What are the causes of type 2 diabetes? What is the relationship between insulin resistance and hyperinsulinemia? W disrupters and what are their functions in our body? Provide some examples. How does concentration of glucose effect insulin secretion? Explain how data from article support or refute the hypothesis that endocrine disrupters can change insulin secretion. Be sure to cite the article in text. Paraphrase key points from the article that support your answers hat are endocrine

Answer 1

causes of type 2 diabetes are family history of diabetes, obesity,lack of exercise and poor eating habits.

Insulin resistance means the cells will not respond to the insulin hence the blood sugar level remains high but in hyperinsulinemia the the insulin level remains high in blood hence it reduce the blood sugar level leads to hypoglycemia.

Endocrine disrupters are some external chemicals which disturbs the normal pathway of the normal which results in abnormal changes and also in some benefits occur.Example for abnormal change is tumour and beneficial change is birth control pills.Diethylstilbestrol,dioxin and polychlorinated diphenyls are some examples of endocrine disrupters.If the glucose levels in blood is low it decrease the stimulation to pancreatic cells thus reduce the insulin secretion suppose if hyperglycemia then the stimulation of pancreatic cells occur thus the insulin secretion increases.Endocrine disrupters are the chemicals which change the normal hormonal pathway so it may also affect the insulin secretion.