Question

28) Explain the key difference between barbiturates and nonbarbiturates. 28) A) Unlike barbiturates, nonbarbiturates are CN S depressants that contain the B) Unlike nonbarbiturates, barbiturates are CNS depressants that contain the C) Barbiturates decrease the activity of GABA, and nonbarbiturates increase the D) None of the above are correct. barbituric acid ring structure in their chemical makeup. barbituric acid ring structure in their chemical makeup. activity of GABA 29) 29) Explain the relationship between gamma-aminobutyric acid and sedative-hypnotic drugs A) Sedative-hypnotic drugs decrease the GABA receptor-mediated potassium influx into nerves, inhibiting neuronal activity B) Seda tive-hypnotic drugs decrease the GABA receptor-mediated chloride influx c) Sedative-hypnotic drugs increase the GABA receptor-mediated sodium influx into D) Sedative-hypnotic drugs increase the GABA receptor-mediated chloride influx into into nerves, enhancing neuronal activity nerves, inhibiting neuronal activity nerves, inhibiting neuronal activity. 30) 30) Select the stage of the sleep cycle that corresponds with the ability to dream. A)REM C) NREM stage I B) NREM stage 2 D) None of the above 31) The binding of the neurotransmitter acetylcholine to the nicotinic-muscle receptors at 31) the neuromuscular junction enables: A) sodium ions to move out of the cells. B) sodium ions to move into the cells. C) magnesium ions to enter the cells D) potassium ions to move into the cells 32) 32) Drugs that inhibit skeletal muscle contraction by blocking conduction within the spinal cord are known as A) cholinergic drugs C) parasympathomimetics B) peripheral skeletal muscle relaxants D) spasmolytics 33) Which of the following statements is true of cholinergic drugs? A) Cholinergic drugs block cholinergic receptors. B) Cholinergic drugs prevent epinephrine from acting upon its receptors. C) Cholinergic drugs stimulate the alpha and beta receptors located on the surfaces of organs. D) Cholinergic drugs stimulate the muscarinic receptors located on smooth and cardiac muscle. 34) What triggers the release of acetylcholine from a neuron? A) Regulator proteins C) Nerve stimulation B) Enzyme activity D) Hormonal inhibition
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Answer 1

28)Barbiturate is a CNS depressant.Agonist of GABA receptor .It is commonly used as anxiolytics,hypnotic and anticonvulsant.They hav a acid ring structure.Non barbiturates are hypnotic drugs and does not have barbuteric acid ring

Ans.b.Unlike non barbiturates, barbiturates are CNS suppressant and contains barbuteric acid ring structure in their chemical make up

29.These drugs bind with the GABA receptor and leading to increase in thw opening of calcium channels andvtherby reducing neuronal activity.

Ans.D)Sedative hypnotic drug increases the GABA receptor mefiated-chloride influx into the nerve, inhibiting neuronal activity

30.The average sleep time is 90 minutes with 4 stages

NREM 1:drowsy can be woken up

NREM 2: falls asleep

NREM 3:deep sleep

NREM 4: Rapid eye movement with dreams occurs here .Individuals can be woken up easily.

Ans.A)REM

31.When binding of neurotransmitter acetylcholine occurs the sodium ions generally move into the cells

Ans.B.Sodium ions yo move into the cells

32.The drugs which are capable of releasing spasm of muscle are called as spasmolytics.They inhibit the contraction of the skeletal muscle by blocking conduction within the spinalcord

Ans.D.Spasmolytic

33.Cholinergic drugs mimic the actions of acetylcholine .It increased the parasympathetic action.It has a ability to stimulate the muscuranic receptor on the smooth and cardiac muscles

Ans.D.Cholinergic drugs stimulate the muscuranic receptor on the smooth and cardiac muscle

34.When the nerves are stimulated The acetylcholine are released

Ans.C.Nerve stimulation