Question

5. a)Predict the results of erythropoietin in a patient with hypoxia.
It will be increased
It will be decreased.
It will be normal.
This cannot be determined.

b) Iron-deficiency anemia can occur from what three mechanisms?
ALAS deficiency, blood loss, decreased transferrin
Mutation of HFE gene, decreased transferrin, increased hepcidin
Inadequate iron intake, impaired iron absorption, decreased hepcidin
Impaired iron absorption, blood loss, inadequate iron intake

c) Pernicious anemia is a malabsorption of vitamin B12 from what component deficiency?
Gastric juice
Folate
Intrinsic factor
Histamine

d)Of the following, who would have the highest concentration of erythropoietin?
A child
A patient who has just donated a kidney
A pregnant mother
An anemic patient

e) All of the following are key components of hematopoietic differentiation except:
The activation of programmed cell death
The formation of mature blood components with a finite life span
The differentiation of blood components when exposed to different cytokines
The commitment to produce blood cells only

f) All of the following disorders would have normal-to-elevated ferritin levels except:
Lead poisoning
Iron-deficiency anemia
Anemia of chronic disease
Sideroblastic anemia

g) Which of the following classes of hematopoietic cells has the ability to self-renew?
Committed myeloid progenitor
Multipotential progenitor cell
Maturing cell
Hematopoietic stem cell

h) A 20-year-old male male medical student with transfusion-dependent thalassemia visits your clinic. He recently learned in his hematology class about thalassemia and iron overload. He asks how to prevent iron overload and liver problems. Which of the following would you recommend for iron overload in patients with transfusion-dependent thalassemia?
Phlebotomy
Iron-chelating medications
Vitamin C
No treatment

i) Regulation of iron entering the body occurs mainly through which mechanism?
Chelation of dietary iron in the intestine
Excretion of excess iron from the intestine into the urine
Absorption of dietary iron into the enterocyte
Transfer of iron in the enterocyte into the blood

Answer 1

5.a.A.it will be increased in hypoxia patient.

b.D.decreased iron absorption,blood loss inadequate iron intake.

C.C.intrinsic factor.

D.D.in anemia erythroprotein concentration will increase.

E.A.

F.A.

G.D.

H.no treatment.

I.c.iron is absorbed from diet to the body.

.