1 )Explain the role of stromal cells in the hematopoietic microenvironment
1 )Explain the role of stromal cells in the hematopoietic microenvironment
HOW POTENT ARE YOUR STEM CELLS? a cell that can produce all the hematopoietic cells in your body: _________ a cell that can develop into a complete adult organism + extraembryonic structures: _________ a cell that develop into a complete adult organism: ________
A hematopoietic cell leads to Stem cells leading to leading to Erythroblast Macrophages and then Platelets Reset Goblet cells Astrocytes Lymphoblast Red blood cells Megakaryocytes Trophoblasts Monocytes Dendritic cells
Monocytes Megakaryocytes Astrocytes Trophoblasts Goblet cells Dendritic cells Red blood cells Lymphoblast 27:11 A hematopoietic cell leads to Stem cell:s leading to leading to Macrophages Erythroblast and then Platelets
Explain the role of innate immune cells such as macrophages and dendritic cells in adaptive immunity in regards to cancer.
Question 1 1 pts Mintz Ellmensee experiment shows that: O a. Solid teratoma cells can behave like embryonic cells if implanted into the microenvironment of blastocyst b. Embryonic cells can behave like solid teratoma if implanted into the microenvironment of blastocyst O c. Solid teratoma cells are cancer cells and behave as cancer cells in any microenvironment O d. Embryonic cells are normal, do not have cancer mutations, and behave as normal cells in any microenvironment C and D are...
Question Set 3 (20 pts) As discussed in class, the pluripotential properties of hematopoietic stem cells (HSCs) were demonstrated by classic studies of marking cells by retroviral transduction and using these cells to reconstitute irradiated mice to make a "bone marrow chimera". Then one assesses fate based on integration sites in the haematopoietically derived cells. Recent studies such as those by Rodriguez-Fraticelli et al. 2018. Clonal Analysis of Lineage Fate in Native Hematopoiesis. Nature 553: 212 (PMC: 5884107) have used...
1)Describe three functions of death receptor induced apoptosis 2)Explain P53’s role in preventing cells with DNA damage from replicating.
A. Match the following cells rith their meanings below: hematopoietic stem cell lymphocyte mопосyte basophil cosinophil erythyocyte neutrophil platelet 1. red blood cell white blood cell: phagocyte and precursor of a macrophage 2. 3. thrombocyte bone marrow cell; gives rise to many types of blood cells 4. 5. leukocyte formed in lymph tissue; produces antibodies 6. leukocyte with dense reddish granules; associated with allergic reactions 7. leukocyte (poly) formed in bone marrow and having neutral-staining granules 8. leukocyte whose granules...
8. Non-hematopoietic cell types are crucial in B cell and T cell development. What/where are these cell types and how do they support development of these lymphocytes? Indicate specifically, what are the molecules/signals that these cells provide?
Question 35 O pts What is the role of dendritic cells in the transition between innate and adaptive immunity? Explain. (This is also a 15-point question) . x x