Question

1. Match the disorder on the left with its pathogenic mechanism on the right. Answers may be used more than once. Some disorders have two answers, and some disorders may have some uncertainty concerning their exact etiology - you may need to do some research to decide what the general consensus is on the cause(s). (6) - Rheumatoid arthritis Asthma Hemolytic disease of the newborn Contact dermatitis A. Type I hypersensitivity B. Type II hypersensitivity C. Type III hypersensitivity D. Type IV hypersensitivity E. Autoimmune EA DOO w Poststreptococcal glomerulonephritis Systemic lupus erythematosus

Answer 1

Hypersensitivity simply means allergy. It is defined as the violent reaction of the immune system leading to severe symptoms and even death in sensitized animal when it is exposed to the same antigen for the second time.

Type 1 anaphylactic hypersensitivity.

Type 2 antibody dependent cytotoxic hypersensitivity.

Type 3 immune Complex mediated hypersensitivity.

Type 4 cell mediated hypersensitivity.

Type 5 stimulated hypersensitivity.

1)Autoimmune (E)- Rheumatoid arthritis.

Autoimmune disorders are are in which antibody has reacted in a damaging way against some body components and that is combined antibody and cell mediated immunity has been made in some organs are cell systems.

2)Type 1 hypersensitivity (A) - asthma.

3)Type 2 hypersensitivity ( B)- hemolytic disease of newborn.

4)Type 4 hypersensitivity (D)- contact dermatitis.

5)Type 3 hypersensitivity (C)- poststreptococcal glumerulonephritis.

6) Autoimmune (E)-systemic lupus erythematosus.