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Roberta Smith (MRN 1234)(Visit 123)(Room 156) is a 56 year old female who has been diagnosed...

Roberta Smith (MRN 1234)(Visit 123)(Room 156) is a 56 year old female who has been diagnosed with Stage 3 bladder cancer. The oncologist has ordered Carboplatin AUC 5 every 21 days x 6 cycles . Carboplatin is available as 10 mg/ml 10 ml vials. Roberta is 65 inches tall and weighs 100 kg. Her serum creatine is 1.2 mg/dl. Please dilute in 100 ml of normal saline.

Med added: Carboplatin

Fluid: 0.9 % sodium chloride

What is the dose (mg) ________

What is the total volume (ml) _________

What is the infusion rate (ml/hr) __________

Schedule every (hours) one time order

How long is this parenteral admixture stable at room temperature. ______

Could your provide the steps for the questions

This is for someone who knows how to do chemistry.

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Answer #1

Carboplatin is available as 10 mg/ml 10 ml vials.

Roberta is 65 inches tall( 165.1cm ) and weighs 100 kg.

#. According to her serum creatinine clearance - 1.2 mg/dl, age, weight and target AUC 5 - her :

GFR - 82.6 ml/min.

DOSE - 538.2 mg

#. Total volume would be using unitary method :-

10mg of carboplatin is present in 1ml

1mg of carboplatin is present in 1ml/ 10mg

538.2 mg of carboplatin will be present in 1ml/10mg × 538.2 mg

= 53.82ml will be the total volume

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