Question

•-Laboratories study of hypothyroidism in relation of medication management •-Hyperthyroid medication mechanism of actions •-Hypoglycemia medication management • Hypothyroid medication teaching

Answer 1

Hyperthroid medications and their mechanism of action?

Hyperthyroid medications are also called Antithroid medication mainly used to prevent the thyroid gland from producing the excess amount of hormone.

The 2 main drugs used are Propylthiouracil and Methimazole

Mechanism of action of propylthiouracil: it acts by inhibiting thyroidperoxidase and hence decreases the T4 production by blocking deiodinase enzyme thereby preventing the conversion of T4 to active T3.

Mechanism of action of Methimazole: It acts by inhibiting the synthesis of throid hormones by blocking the oxidationof iodine in the thyroid gland. Iodine is not available to combine with throsine to form thryroxine and triiodothyronine(T3) it doesnot inactivate circulating T4 and T3.

Hypoglycemia medical management

Dextrose: 20-50ml of 50% dextrose or 50-100ml 0f 25% dextrose. May repeat after 15 minutes according blood sugar level.

Glucagon: 1mg IV/IM/SC once if weight >20kg and 0.5mg if weight <20 kg.

Health education for patient taking hypothroid medication

a) Should take tablet at the same time everyday on e,mpty stomach

b) take with full glass of water

c) Dont stop medicine without the physicians advise

e) Donot take cacium or iron within 4 hours of taking thyroid medication.

f) Notify to physician if there is any change in medication due to any disease.