Question

In general, which organ must be functioning for proper excretion?

Question 8 options:

	The heart
	The kidneys
	The liver
	The brain

In general, which organ must be function for proper metabolism of drugs?

Question 9 options:

	The liver
	The kidneys
	The heart
	The brain

True or False, if either of the organs that were answers to the previous two questions are not fully functioning, the patient's response to medication may be altered.

Question 10 options:

	True
	False

Who is MOST at risk for having alterations in liver or kidney function?

Question 11 options:

	A 3 day old female
	A 46 year old male
	A 99 year old male
	Both 1 and 3

Match the following term with the definition.

Question 12 options:

123456 The movement of the drug from the blood to the interstitial space of tissue and into the cell 123456 What the drug does to the body 123456 The movement of the drug from the site of administration to the blood 123456 Bio transformation, alteration of drug structure 123456 Movement of drug and metabolites out of the body 123456 The study of drug movement through the body

1. Pharmacokinetics 2. Pharmacodynamics 3. Absorption 4. Distribution 5. Metabolism 6. Excretion

The APRN has ordered Lisinopril 10mg, PO, PRN daily. The nurse knows this medication will be administered how?

Question 13 options:

	IV
	Rectally
	Topically
	By mouth

Which form of administration offers the most complete absorption?

Question 14 options:

	IV
	PO
	Rectal
	Topical

Opioids turn on mu receptors allowing them to affect pain. Opioids are _____ to mu receptors.

Question 15 options:

	Similar
	Agonist
	Antagonist
	opposite

Question 16 (1 point)

Narcan binds to mu receptors blocking them from being bound and therefore blocking their normal function. Narcan is _______ to mu receptors.

Question 16 options:

	An agonist
	An antagonist
	Similar
	Opposite

Which drug would most easily travel throughout the body?

Question 17 options:

	A lipid soluble drug
	A water soluble drug
	A large drug
	A STAT drug

You are the nurse preparing to administer a medication with a small therapeutic range. What is your priority?

Question 18 options:

	Monitor for therapeutic effects
	Monitor for adverse effects
	Question the order
	Both 1 and 2

Match the name with the name type.

Question 19 options:

123 Chemical 123 Generic 123 Brand

1. Tylenol 2. N-(4-hydroxyphenyl)ethanamide 3. acetaminophen

This term describes a process that causes causes rapid hepatic inactivation of certain oral drugs.

Question 20 options:

	Enterohepatic Recirculation
	First Pass Effect
	Half Life
	CY P450

This term refers to a process that allows drugs to a process that allows a drug to stay in the body for longer.

Question 21 options:

	Enterohepatic recirculation
	First pass effect
	Half life
	CY P 450

What is the group of enzymes that often affects metabolism of drugs called?

Question 22 options:

	CY P450
	DY P450
	BY 123
	D

You are administering a drug with a half life of 1 hour. You initially give 100mg. How much remains after 2 hours?

Question 23 options:

	50mg
	25mg
	200mg
	0mg

Answer 1

1. The kidneys must be functioning for proper excretion. Excretion is the function of kidney.

2. Liver must be function for proper metabolism of drugs. Detoxification is one of the functions of liver.

3. The statement is true. If Kidneys and liver are not fully functioning, the patient's response to medication may be altered.

4. A 3 days old female and 99 years old male are at most risk for having alterations in kidney and liver functions.