Question

Case 2 A 45-year-old woman presents to an urgent care center complaining of pruritic hives after being stung by a bee. She takes propranolol, 80 mg twice a day, for hypertension. She is given epinephrine 0.3 mg sc, and diphenhydramine, 50 mg iv. 1. What is the expected response to epinephrine? To diphenhydramine? 2. How might propranolol alter these responses?

Answer 1

→ ⓘ Expected response of epinephrine:- -T+ ic used -for allergic reactions Veins an sect to increase blood flow throunh reduce Supeltng in aiway pinephine is onlya temperary tr or allergic reaction expectedl response is that it causes consictio or tightening of the blooel vessels wohi ch decreatet Suve lting and alko help to incrcae blood pre.ture E pinephvine is recognised by veceptort n Smooth musles it causes air-voay blockin g murcle cons hiction to Subsidc Expected respone -to cdiphenhydlramine Provides local relief from sting bite ,poss ibly due to an anesthetic effect resulting fro decreased perme ability of nerve cell membrane to Sedium ions (preventing the tsanmiction of nerve im pulie ⑧ propranolol bloc t l the effecti of epinephrine propronolol makei your heavt beats slouol more Sloroly thercby redlucing blood pressure propranolol binds oith high affinity to both beta-I and beta- out has fovo affinity at beta- propranolol exerts its effect primarit caY oLo the action of endogen oot catecholamines at beta adrenernic recepoys y by blocting ner, e pineph ine eneraic reccptor