hepatic clearance of 5-flurouracil
V = 18L
t1/2 11 min
so by the end of 5 th half it will be come down to 90% and the fex will be <1%
so the time taken will be 11*5 = 55minutes
Calculate the hepatic clearance (Umin) of the drug 5-fluorouracil (fus 90%; fex < 196; V-18 L...
Typical pharmacokinetic parameters of DRUG-A are F-0.02; fex < 0.1; fu 0.3; V- 0.22 L/Kg Half-life 4 hours. Drug-A is administered as a continuous IV-Infusion to a patient taking another medication that is known to induce the hepatic-metabolism of Drug-A. Therefore, the time to reach steady state will: D Increase 0 Decrease O Show little difference
Hepatic Clearance Practice Problems PH4330 1. Normal CL value for this drug is 0.5 L/min and elimination is via the liver. V 100 L a. Is this a low, intermediate, or high E drug? b. In CHF (congestive heart failure) patient, Q is half the normal value of 800 ml/min. What would the hepatic clearance be in the CHF patient? What would be the normal and CHF FFp values? c. 2. Given the following pharmacokinetic information for a drug: .Q...
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< Question 34 of 65 > Calculate the volume, in liters, occupied by 0.165 mol of oxygen gas at STP. L V=
• Consider a production function f(21,22) = min{21,22}: - When I1 < 12, please calculate the marginal product of 11 and 12. If there is a small increment in 11, then re-calculate the marginal product of 21 and 22. - When I1 = 12, please calculate the marginal product of 11 and 12. If there is a small increment in 21, then re-calculate the marginal product of 21 and 22.
< Question 18 of 28 > Calculate the molarity of 0.550 mol of Na,S in 1.20 L of solution. I molarity: М Calculate the molarity of 25.9 g of MgS in 959 mL of solution. molarity: М careers privacy policy tens of use contact us help about us 523 P D 4 d 11/17/2 od Mome Prsen
A clinical trial was conducted to test the effectiveness of a drug used for treating insomnia in older subjects. After treatment with the drug, 22 subjects had a mean wake time of 94.6 min and a standard deviation of 41.5 min. Assume that the 22 sample values appear to be from a normally distributed population and construct a 90% confidence interval estimate of the standard deviation of the wake times for a population with the drug treatments. Does the result...
u =<4, -5 > v=<3, 2 > | 2u – vl = ? Whole number. <7, -1, 5 >.< 2, 3, 1>=? whole number
Question 1 5 pts What is the name of the slope of the isoquant? No abbreviations. 12pt Paragraph BI V A L T Owords </> Question 2 5 pts Write down the equation that decomposes the effect of a change in price on demand of a good. No abbreviations. 12pt Paragraph BI V Ave Tv
Calculate V-3+ 3i. Give your answer in a + bi form. In polar form, use the angle 0 <o<27. Submit Question