Question

MYCOLOGY CASE STUDIES THESE CASE STUDIES MUST BE SUBMITTED WITH THE MYCOLOGY LAB OR MY WILL NOT BE GRADED. CASE STUDY #1 A young woman in Southern Florida desired a fashionable suntan. The result she had anticipated. Her tan appeared uneven with well outlined, hypo her upper torso. Her dermatologist performed a microscopic examination of skin scales using potassium hydroxide solution and observed yeast cells and hyphae resembling "spaghetti and s were not what pigmented lesions on meatballs" 1. The history and examination are consistent with a preliminart diagnosis of A. candidiasis B. tinea unguium C. ringworm D. tinea versicolor E. sporotrichosis 2. Which is the most appropriate nutrient media for culturing this organism? A. Conradi Drigalski agar B. Lowenstein Jensen medium C. Mueller Hinton medium D. Nutrient blood agar E. Sabouraud's agar 3. An antifungal compound of choice for treating the infection is: A. salicylic acid B. zinc oxide C. tolnaftate D. miconazole E. undecylenic acid 4. The organism responsible for this infection is: A. Cladosporium wernecki B. Trichosporon cutaneum C. Piedra hortae D. Pityrosporium orbiculare E. Sporothrix schencki

Answer 1

Fungal infection of skin causing pigmentary changes and scaling of the skin is seen in Tinea versicolor. In this type of infection fungi produce enzymes that inhibit melanin production . The lesions are asymptomatic and appear as patches with fine scales.

The causative organism is the yeast Pityrosporium orbiculare. Microscopic examination of slides with potassium hydroxide shows combination of fungal yeast and hyphae forms in a " spaghetti and meatball appearance with superficial layers of the epidermis.

So, the answer to your questions is

1. the history and examination are consistent with the preliminary diagnosis of D) tinea versicolor
2. The most appropriate nutrient media for culturing this organism is E)Sabouraud's agar as it consists of nutrients and trace elements required for the growth of most of the yeast and fungi.
3. Antifungal topical azoles mostly imidazoles like ( flutrimazole, ketoconazole, miconazole , econazole) are used for the treatment of tinea versicolor. So the answer is D)Miconazole
4. The organism responsible for tinea versicolor isD) Pityrosporium orbiculare

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