Question

Antipsychotics carry a risk of EPS (extrapyramidal side effects). Conduct some research online. Go out to websites, you tube, etc. and find several comprehensive samples that show/discuss EPS. Bring back the one URL to the information you think is the best and share it with your peers

Answer 1

ANS) The Antipsychotic drugs are the keystone of the pharmacological medical care of the Schizophrenia.And the establishment of the primary antipsychotic chlorpromazine in the year 1952 pointed the new period in the psychopharmacology.

-- Anyway that old antipsychotics,presently known as the first generation antipsychotics ,like the chlorpromazine,haloperidol,even though very successful in reducing the positive signs of the disorder,have little major restrictions.And the absence of effectiveness concerning negative signs and unfavourable effects,mainly extrapyramidal symptoms or EPS are the major disadvantage of these kind of drugs.

-- The EPS involve severe dystonias,parkinsonism and the tardive dyskinesia(TD).The EPS are very significant occasionally exhausting and denouncing adverse effects and need extra pharmacotherapy. This EPS will be growing to 2 stages.Early,severe EPS more often grow upon the starting of the medical care or treatment and exist as TD or tardive dyskinesia. The motor demonstration involve akathisia, that means restlessness and pacing, the muscle spams or the severe dystonia and skeletal muscle stiffness(Parkinsonism).

-- The TD is mainly distinguished by involuntary,monotonous facial motions like as the grimacing,sticking out of tongue, wrinkled lip and also the oculogyric crisis.And we can say that the severe EPS is the major reason for poor attachment to the antipsychotic medical care because of the reversibility of signs or symptoms,while the late TD is having the more major influence on the patients and the care giving persons in the regard to standard of life.

-- The TD sometimes persevere after the stopping of treatment.It is calculated that around 50% of the clients are mainly treated with large strength FGAs grow severe EPS in the early times of the treatment .The commonness of the TD in the survey has registered to be 0.5% - 70% of the patients getting FGAs.

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