Question

For Ondansetron Hcl

Use this Guide as you research your medications and then as you enter your findings in DocuCare. Type the numbers 1 through 12 [ a), b), c), d), e) ] into the Protocol/Note: Window which is at the bottom of Add New Medication Order 1. Medication Order (written the way the MD/NP ordered it) drug-dose -route -frequency 2. generic name: 3. Trade name: 4. Maximum Safe Dose in 24 hours: 5. Therapeutic class/Pharmacologic classification: 6. Indication 7. Black Box Warning: (if none- type None) 8. Common Adverse Reactions (maximum - 8) 9. Life Threatening Adverse Reactions: (If none -type None) 10. Drug-Drug Interactions (Only list those that apply for your patient & type the interaction & nursing considerations) - If there are none Type None 11. Food-Drug Interactions (Only list those that may apply for your patient) 12. Nursing Considerations (Individualized to your patient) a) Assess (what to assess prior to administration) - 6th Pt Right - Right Assessment b) Administration -technique (P.O., I.V. etc.) c) Following administration-> monitor for (Common Adverse Effects, Life Threatening Effects) d) Evaluate for the Therapeutic effect-> (i.e. blood pressure within normal range) e) Pt specific teaching

Answer 1

Drug - Ondansetron

1. Medication order - 2mg/ml IV , 4mg/ 8mg tablet orally ,4mg/8mg oral dissolving film, 4mg/8mg oral disintegrating tablets , 2mg/5ml oral solution .

2. Generic name - Ondansetron and Ondansetron hydrochloride

3. Trade name - Zofran

4. Maximum safe dose in 24 hours - 24 mg

5. Func. class.: Antiemetic

Chem. class.: 5-HT3 receptor antagonist

# Action of this medication

Prevents nausea, vomiting by blocking serotonin peripherally, centrally, and in the small intestine

6. Indications for the use of this medication :-

Prevention of nausea, vomiting associated with cancer chemotherapy, radiotherapy; prevention of postoperative nausea, vomiting.

7. None

9. Life threatening adverse reactions/side effects

bronchospasm (rare)

8. Common adverse reactions/side effects

Headache, dizziness, drowsiness, fatigue, EPS

musculoskeletal pain, wound problems, shivering, fever, hypoxia, urinary retention.

10. Drug interactions

Amiodarone and other class III anti arrhythmic agents can cause dose-related prolongation of the QT interval.

11. Drug-Lab-Food Interactions

Lab-increase bilirubin, AST and ALT Levels (increase could detect liver damage). Ginger may increase bleeding with anticoagulants.

12. Nursing Interventions and Considerations

.Assess: history of onset, frequency, amount and contents of vomitus.

Concerns: daily dose not exceed 8mg.

Assess: History: heart disease, chest pain or liver disease.

History: of onset, frequency and amount of contents of vomitus and length of time taking Ondansetron.

Monitor: vital signs, labs-increase in bilirubin, AST & ALT levels;

Isolation if secondary to C-diff.

For chemotherapy give antiemetic 30 to 60 minutes before therapy.

#. Client Education

Teach: avoid alcohol, causes intensify sedative effect; teach client and family about contact precautions for C-diff. Client with liver disease (daily dose not to exceed 8 mg).