Question

The advantage (s) of RNAi-based therapeutics over traditional treatment approaches Highly specific b. Bypasses resistance to traditional drug 4 а. Both a and b C. None of the above d. Which of the following chemical modifications help to stabilize siRNA against endonucleases? a. Addition of 2'-O-Methyl groups b. Addition of 2'-fluoride groups 5 Both a and b C. d. None of the above Stable introduction of a gene into the genetic complement of a cell, such that subsequent expression of the gene achieves a therapeutic goal is called Gene therapy b. Human gemone project а. genomics с. None of the above d.

Answer 1

4)RNAi is highly specific and also bypasses the resistance to the traditional drugs.

So answer is C.

5)Stability is due to the addition of 2'-O methyl groups.

So answer is B.

6)Introduction of a gene into an organism so that the gene expresses the protein and the synthesized proteins achieve a therapeutic goal is called gene therapy.It is used in the treatment of gene deficinecy diseases.

So answer is A.