Question

Q7. What is the pharmacological action of Donepezil? A) ACHE activator b) AChE inhibitor C) NMDA receptor inhibitor inflammation D) Inhibitor of neural 08. A 78 YOF is suffering from middle stages of Alzheimer's disease. She is prescribed a cholinesterase inhibitor. Which of the following choices below belong to this class of drugs? A) MEMANTINE B) Rivastigmine C) Rasagiline D) Entacapone E) Bromocriptine

Answer 1

QUESTION: 7

ANSWER: B) Acetylcholine inhibitor

  Donepezil (aricept).It is used to treat Alzheimer's disease.It binds and inactivates the cholinesterases, thus inhibiting the acetylcholine. The common side effects includes nausea, muscle cramps, diarrhea, feeling tired and aggression.It should be used with caution in people with heart diseases, chronic obstructive pulmonary disease, cardiac arrhythmias and pulmonary disease.

QUESTION: 8

ANSWER:B) Rivastigmine

In the people with Alzheimer's disease, nerve cells are less active.The brain signals takes longer time for the transmission of signals. Cholinesterase inhibitors helps to increase the communication between the nerve cells and helps to improve the symptoms of Alzheimer's disease.It provides positive effect on cognitive performance. Donepezil, galantamine and rivastigmine can delay the loss of mental abilities in the people with mild to moderate Alzheimer's disease.The clients who consume this medication were able to remember things more easily.